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Can the venerated silk be the next-generation nanobiomaterial for biomedical-device designing, regenerative medicine and drug delivery? Prospects and hitches
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Rocktotpal Konwarh. Can the venerated silk be the next-generation nanobiomaterial for biomedical-device designing, regenerative medicine and drug delivery? Prospects and hitches[J]. Journal of Zhejiang University Science D, 2019, 2(4): 278-286.
@article{title="Can the venerated silk be the next-generation nanobiomaterial for biomedical-device designing, regenerative medicine and drug delivery? Prospects and hitches",
author="Rocktotpal Konwarh",
journal="Journal of Zhejiang University Science D",
volume="2",
number="4",
pages="278-286",
year="2019",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-019-00052-9"
}
%0 Journal Article
%T Can the venerated silk be the next-generation nanobiomaterial for biomedical-device designing, regenerative medicine and drug delivery? Prospects and hitches
%A Rocktotpal Konwarh
%J Journal of Zhejiang University SCIENCE D
%V 2
%N 4
%P 278-286
%@ 1869-1951
%D 2019
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-019-00052-9
TY - JOUR
T1 - Can the venerated silk be the next-generation nanobiomaterial for biomedical-device designing, regenerative medicine and drug delivery? Prospects and hitches
A1 - Rocktotpal Konwarh
J0 - Journal of Zhejiang University Science D
VL - 2
IS - 4
SP - 278
EP - 286
%@ 1869-1951
Y1 - 2019
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-019-00052-9
Abstract: Of late, the relevance of silk in a myriad of material science and biotechnological realms has been realized, as attested by the incessantly clambering number of reports and patents in the scientific repositories. The write-up is geared off with a scrutiny into the pertinence of the basic nano-structural features of silk, christened as the ‘queen of textile’ for exemplary bioengineering applications including designing and fabrication of devices for microfluidics, optofluidics, chemo/bio sensing, etc. Then, the major thrust of this short review is directed towards comprehending the prospects of using silk-based biomaterials (e.g. scaffolds, electrospun membranes, films, hydrogels, bioinks) for tissue engineering and regenerative medicine as well as targeted delivery of various biomolecular cargoes/therapeutic agents, etc., as vouched by few avant-garde endeavours of the recent years. The write-up is entwined with a discussion on the various factors that could plausibly hinder the realization of silk as the next-generation nanobiomaterial, suggestions for some approaches to dodge and deal with the practical snags and what lies ahead!
Open peer comments: Debate/Discuss/Question/Opinion
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