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CLC number: R595.9
On-line Access: 2018-02-06
Received: 2017-11-15
Revision Accepted: 2018-01-25
Crosschecked: 2018-01-08
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HIV and paraquat poisoning: fighting fire with fire?
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Yuan-qiang Lu. HIV and paraquat poisoning: fighting fire with fire?[J]. Journal of Zhejiang University Science B, 2018, 19(2): 168-170.
@article{title="HIV and paraquat poisoning: fighting fire with fire?",
author="Yuan-qiang Lu",
journal="Journal of Zhejiang University Science B",
volume="19",
number="2",
pages="168-170",
year="2018",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1700567"
}
%0 Journal Article
%T HIV and paraquat poisoning: fighting fire with fire?
%A Yuan-qiang Lu
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 2
%P 168-170
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1700567
TY - JOUR
T1 - HIV and paraquat poisoning: fighting fire with fire?
A1 - Yuan-qiang Lu
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 2
SP - 168
EP - 170
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1700567
Abstract: Though the cases of HIV patients with paraquat (PQ) poisoning are rare, we still found the common features. These recovered HIV patients tended to result in much less lung injury, and had low CD4+ T lymphocyte levels due to HIV infection, which meant they were under the immunosuppressive condition during treatment. This may be conducive to relieve the acute inflammation and lung fibrosis induced by PQ. Thus, we consider the immunosuppressive therapy for PQ poisoning to be appropriate. However, the drugs used currently may be not optimal for toxic patient. As next step, we will add the CD4+ T lymphocyte-targeted immunosuppressive drug to treat PQ poisoning patients.
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