Affiliation(s):
School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China;
moreAffiliation(s): School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China; Department of Nephrology, Yantai Yuhuangding Hospital, Qingdao University, Yantai 264005, Shandong, PR China; Institute of Crop Science, College of Agriculture and Biotechnology, Zhejiang University, Zijingang Campus, Hangzhou 310058, PR China;
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Xiaoxuan FU, Peng LI, Xi CHEN, Yuanyuan MA, Rong WANG, Wenxuan JI, Jiakuo GU, Bowen SHENG, Yizhou WANG, Zhuhong ZHANG. Ceria nanoparticles: biomedical applications and toxicity[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2300854
@article{title="Ceria nanoparticles: biomedical applications and toxicity", author="Xiaoxuan FU, Peng LI, Xi CHEN, Yuanyuan MA, Rong WANG, Wenxuan JI, Jiakuo GU, Bowen SHENG, Yizhou WANG, Zhuhong ZHANG", journal="Journal of Zhejiang University Science B", year="in press", publisher="Zhejiang University Press & Springer", doi="https://doi.org/10.1631/jzus.B2300854" }
%0 Journal Article %T Ceria nanoparticles: biomedical applications and toxicity %A Xiaoxuan FU %A Peng LI %A Xi CHEN %A Yuanyuan MA %A Rong WANG %A Wenxuan JI %A Jiakuo GU %A Bowen SHENG %A Yizhou WANG %A Zhuhong ZHANG %J Journal of Zhejiang University SCIENCE B %P %@ 1673-1581 %D in press %I Zhejiang University Press & Springer doi="https://doi.org/10.1631/jzus.B2300854"
TY - JOUR T1 - Ceria nanoparticles: biomedical applications and toxicity A1 - Xiaoxuan FU A1 - Peng LI A1 - Xi CHEN A1 - Yuanyuan MA A1 - Rong WANG A1 - Wenxuan JI A1 - Jiakuo GU A1 - Bowen SHENG A1 - Yizhou WANG A1 - Zhuhong ZHANG J0 - Journal of Zhejiang University Science B SP - EP - %@ 1673-1581 Y1 - in press PB - Zhejiang University Press & Springer ER - doi="https://doi.org/10.1631/jzus.B2300854"
Abstract: Cerium oxide nanoparticles (CeO2 NPs) have become popular materials in biomedical and industrial fields due to their potential applications in anti-oxidation, cancer therapy, photocatalytic degradation of pollutants, sensors, etc. Many methods, including gas phase, solid phase, liquid phase, and the newly proposed green synthesis method, have been reported for the synthesis of CeO2 NPs. Due to the wide application of CeO2 NPs, concerns about their adverse impacts on human health have been raised. This review covers recent studies on the biomedical applications of CeO2 NPs, including their use in the treatment of various diseases (e.g., Alzheimer’s disease, ischemic stroke, retinal damage, chronic inflammation, and cancer). CeO2 NP toxicity is discussed in terms of the different systems of the human body (e.g., cytotoxicity, genotoxicity, respiratory toxicity, neurotoxicity, and hepatotoxicity). This comprehensive review covers both fundamental discoveries and exploratory progress in CeO2 NP research that may lead to practical developments in the future.
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