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Received: 2007-01-04

Revision Accepted: 2007-03-14

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Journal of Zhejiang University SCIENCE B 2007 Vol.8 No.5 P.314-317

http://doi.org/10.1631/jzus.2007.B0314


Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel mapping


Author(s):  TIAN Yong, LU Li-zhi, FU Yan, TAO Zheng-rong, SHEN Jun-da, WANG De-qian, YUAN Ai-ping, YIN Zhao-zheng

Affiliation(s):  Laboratory of Animal Genetics, College of Animal Sciences, Zhejiang University, Hangzhou 310029, China; more

Corresponding email(s):   yzhzh@zju.edu.cn

Key Words:  Radiation hybrid panel, Mapping, CCR7 gene, Chicken


TIAN Yong, LU Li-zhi, FU Yan, TAO Zheng-rong, SHEN Jun-da, WANG De-qian, YUAN Ai-ping, YIN Zhao-zheng. Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel mapping[J]. Journal of Zhejiang University Science B, 2007, 8(5): 314-317.

@article{title="Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel mapping",
author="TIAN Yong, LU Li-zhi, FU Yan, TAO Zheng-rong, SHEN Jun-da, WANG De-qian, YUAN Ai-ping, YIN Zhao-zheng",
journal="Journal of Zhejiang University Science B",
volume="8",
number="5",
pages="314-317",
year="2007",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2007.B0314"
}

%0 Journal Article
%T Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel mapping
%A TIAN Yong
%A LU Li-zhi
%A FU Yan
%A TAO Zheng-rong
%A SHEN Jun-da
%A WANG De-qian
%A YUAN Ai-ping
%A YIN Zhao-zheng
%J Journal of Zhejiang University SCIENCE B
%V 8
%N 5
%P 314-317
%@ 1673-1581
%D 2007
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2007.B0314

TY - JOUR
T1 - Assignment of CCR7 gene to chicken chromosome 27 by radiation hybrid panel mapping
A1 - TIAN Yong
A1 - LU Li-zhi
A1 - FU Yan
A1 - TAO Zheng-rong
A1 - SHEN Jun-da
A1 - WANG De-qian
A1 - YUAN Ai-ping
A1 - YIN Zhao-zheng
J0 - Journal of Zhejiang University Science B
VL - 8
IS - 5
SP - 314
EP - 317
%@ 1673-1581
Y1 - 2007
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2007.B0314


Abstract: 
The protein encoded by CC chemokine receptor 7 (CCR7) is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. To map the CCR7 gene in chicken chromosome, a 6 000 rads chicken-hamster radiation hybrid panel (ChickRH6) was used. PCR of samples from ChickRH6 revealed that the location of CCR7 gene is linked to the maker SEQ0347 (6 cR away) with LOD score of 16.6 and that the marker SEQ0347 is located on chromosome 27 at 27 cR of RH (radiation hydrid) map. We compared the corresponding human mRNA sequence with the predicted coding sequence of chicken CCR7 gene, and found that the assembled contig shared a high percentage of similarity with that of the human gene.

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Reference

[1] Dieu, M.C., Vanbervliet, B., Vicari, A., Bridon, J.M., Oldham, E., Ait-Yahia, S., Briere, F., Zlotnik, A., Lebecque, S., Caux, C., 1998. Selective recruitment of immature and mature dendritic cells by distinct chemokines expressed in different anatomic sites. J. Exp. Med., 188(2):373-386.

[2] Dijkstra, I.M., de Haas, A.H., Brouwer, N., Boddeke, H.W., Biber, K., 2006. Challenge with innate and protein antigens induces CCR7 expression by microglia in vitro and in vivo. Glia, 54(8):861-872.

[3] Iijima, N., Yanagawa, Y., Clingan, J.M., Onoe, K., 2005. CCR7-mediated c-Jun N-terminal kinase activation regulates cell migration in mature dendritic cells. Int. Immunol., 17(9):1201-1212.

[4] Jang, M.H., Sougawa, N., Tanaka, T., Hirata, T., Hiroi, T., Tohya, K., Guo, Z., Umemoto, E., Ebisuno, Y., Yang, B.G., et al., 2006. CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes. J. Immunol., 176(2):803-810.

[5] Lipp, M., Muller, G., 2003. Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking. Verh. Dtsch. Ges. Pathol., 87:90-101.

[6] Morisson, M., Lemiere, A., Bosc, S., Galan, M., Plisson-Petit, F., Pinton, P., Delcros, C., Feve, K., Pitel, F., Fillon, V., et al., 2002. ChickRH6: a chicken whole-genome radiation hybrid panel. Genet. Sel. Evol., 34(4):521-533.

[7] Murphy, P.M., Baggiolini, M., Charo, I.F., Hebert, C.A., Horuk, R., Matsushima, K., Miller, L.H., Oppenheim, J.J., Power, C.A., 2000. International union of pharmacology. XXII. Nomenclature for chemokine receptors. Pharmacol. Rev., 52(1):145-176.

[8] Okada, T., Cyster, J.G., 2007. CC chemokine receptor 7 contributes to Gi-dependent T cell motility in the lymph node. J. Immunol., 178(5):2973-2978.

[9] Otero, C., Groettrup, M., Legler, D.F., 2006. Opposite fate of endocytosed CCR7 and its ligands: recycling versus degradation. J. Immunol., 177(4):2314-2323.

[10] Riol-Blanco, L., Sanchez-Sanchez, N., Torres, A., Tejedor, A., Narumiya, S., Corbi, A.L., Sanchez-Mateos, P., Rodriguez-Fernandez, J.L., 2005. The chemokine receptor CCR7 activates in dendritic cells two signaling modules that independently regulate chemotaxis and migratory speed. J. Immunol., 174(7):4070-4080.

[11] Rollins, B.J., 1997. Chemokines. Blood, 90(3):909-928.

[12] Rossi, D.L., Vicari, A.P., Franz-Bacon, K., McClanahan, T.K., Zlotnik, A., 1997. Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta. J. Immunol., 158(3):1033-1036.

[13] Sallusto, F., Lanzavecchia, A., 2000. Understanding dendritic cell and T-lymphocyte traffic through the analysis of chemokine receptor expression. Immunol. Rev., 177(1):134-140.

[14] Sallusto, F., Schaerli, P., Loetscher, P., Schaniel, C., Lenig, D., Mackay, C.R., Qin, S., Lanzavecchia, A., 1998. Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur. J. Immunol., 28(9):2760-2769.

[15] Schweickart, V.L., Raport, C.J., Godiska, R., Byers, M.G., Eddy, R.L.Jr, Shows, T.B., Gray, P.W., 1994. Cloning of human and mouse EBI1, a lymphoid-specific G-protein-coupled receptor encoded on human chromosome 17q12-q21.2. Genomics, 23(3):643-650.

[16] Willimann, K., Legler, D.F., Loetscher, M., Roos, R.S., Delgado, M.B., Clark-Lewis, I., Baggiolini, M., Moser, B., 1998. The chemokine SLC is expressed in T cell areas of lymph nodes and mucosal lymphoid tissues and attracts activated T cells via CCR7. Eur. J. Immunol., 28(6):2025-2034.

[17] Yoshida, R., Imai, T., Hieshima, K., Kusuda, J., Baba, M., Kitaura, M., Nishimura, M., Kakizaki, M., Nomiyama, H., Yoshie, O., 1997. Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7. J. Biol. Chem., 272(21):13803-13809.

[18] Yoshida, R., Nagira, M., Kitaura, M., Imagawa, N., Imai, T., Yoshie, O., 1998. Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7. J. Biol. Chem., 273(12):7118-7122.

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