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On-line Access: 2022-12-15
Received: 2022-06-29
Revision Accepted: 2022-08-11
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Citations: Bibtex RefMan EndNote GB/T7714
Rui HUANG, Pan LIU, Yiguang BAI, Jieqiong HUANG, Rui PAN, Huihua LI, Yeping SU, Quan ZHOU, Ruixin MA, Shaohui ZONG, Gaofeng ZENG. Changes in the gut microbiota of osteoporosis patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2200344 @article{title="Changes in the gut microbiota of osteoporosis patients based on 16S rRNA gene sequencing: a systematic review and meta-analysis", %0 Journal Article TY - JOUR
基于16S rRNA基因测序技术揭示骨质疏松症患者肠道菌群的改变:一项系统评价和荟萃分析1广西医科大学公共卫生学院,广西南宁,530021 2广西医科大学第一附属医院脊柱骨科,广西南宁,530021 3广西南宁市第一人民医院创面修复科,广西南宁,530022 4新乡医学院第三附属医院骨科,河南新乡,453000 5川北医学院第二临床医学院,南充市中心医院骨科,四川南充,637000 概要:骨质疏松症(osteoporosis,OP)已成为严重威胁全球中老年人骨健康的重大公共卫生问题。肠道菌群(gut microbiota,GM)的改变与维持骨量和骨质量有关。然而,相关研究结果仍存在很大争议,目前尚没有研究对肠道菌群和骨质疏松间关系进行过系统评价和荟萃分析。本研究通过对骨质疏松症患者和健康人群之间肠道菌群差异的既往16S rRNA基因测序结果进行系统评价和荟萃分析,以期为未来个体化预防和治疗骨质疏松症提供新的临床参考。这项观察性的荟萃分析显示,肠道菌群的改变与骨质疏松症之间存在关联,并且一些优势菌群的变化可能存在地域差异。 关键词组: Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article
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