Abstract: The short report will be focused on the genetic basis and possible mechanisms of tumorigenesis, common types of cancer, the importance of genetic diagnosis of cancer, and the methodology of cancer genetic diagnosis. They will also review presymptomatic testing of hereditary cancers, and the application of expression profiling to identify patients likely to benefit from particular therapeutic approaches.

Key words: Cancer genetics, Oncogenes, Tumor suppress genes, Microarray CGH (comparative genomic hybridization), Presymptomatic testing

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