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Journal of Zhejiang University SCIENCE A

ISSN 1673-565X(Print), 1862-1775(Online), Monthly

Elliptical ultrasonic side milling for improved surface integrity and fatigue resistance of thin-walled Ti6Al4V components

Abstract: Ti6Al4V alloy is critical for thin-walled aerospace components, yet conventional methods for its surface enhancement struggle to balance efficiency and precision. While ultrasonic vibration milling has been demonstrated to improve fatigue performance, its strengthening mechanism requires further investigation. Additionally, its application in fatigue-critical side milling remains underexplored. To address this gap, we introduce the method of ultrasonic peening side milling (UPSM), which integrates elliptical vibration into side milling to achieve simultaneous machining and surface strengthening. Theoretical and finite element analyses are performed to elucidate the mechanisms of residual stress generation and plastic deformation in UPSM and two-pass UPSM (TUPSM). Our experimental results demonstrate that the UPSM method reduces surface defects. At a vibration amplitude of 8 μm, UPSM increases the surface residual compressive stress by 47.4% and the thickness of subsurface plastic deformation layer by 91.5% as compared to conventional milling (CM). TUPSM amplifies these effects, achieving a 55.5% increase in residual compressive stress. Fatigue tests reveal 3.38-fold (for UPSM) and 3.76-fold (for TUPSM) improvement in fatigue life over CM, a phenomenon which is attributed to the subsurface crack initiation and grain refinement induced by ultrasonic ironing and impact effects. This work establishes UPSM as an integrated and cost-effective solution for enhancing fatigue performance in thin-walled Ti6Al4V components, overcoming the limitations of conventional methods and advancing between precision machining and strengthening treatments.

Key words: Ultrasonic peening side milling (UPSM); Ti6Al4V; Surface integrity; Fatigue performance; Thin-walled components

Chinese Summary  <3> TRPV1:从结构到功能--多维度治疗靶点的研究进展

刘毅1,2, 段福芹1,2, 林润鹏1,2, 苏比努尔·沙布尔江1,2, 杨帆4,5, 阿尔孜古丽·艾尔肯1,2,3
1新疆医科大学基础医学院生理学教研室, 中国乌鲁木齐市, 830017
2新疆地方病分子生物学重点实验室, 中国乌鲁木齐市, 830017
3新疆医科大学校级科研平台神经生理基础与临床转化重点实验室, 中国乌鲁木齐市, 830017
4浙江大学医学院生物物理系, 浙江大学附属第一医院肾脏病中心, 中国杭州市, 310058
5良渚实验室, 中国杭州市, 311121
摘要:瞬时受体电位香草素亚型1(transient receptor potential vanilloid subtype 1,TRPV1)是一种多模态激活的钙离子通透性非选择性阳离子通道蛋白,广泛分布于全身各部位,在伤害感觉神经元中表达显著。该离子通道在生理与病理状态下均发挥关键作用,不仅介导多种刺激的应答反应,还参与维持机体稳态。TRPV1凭借其对温度变化、化学配体及电压波动的独特响应能力,成为理解与调控正常生理功能的关键靶点,同时也为疾病诊断与治疗提供重要依据。本文系统综述了TRPV1的结构、门控机制及其生理和病理作用,强调了其在多种疾病中的潜在治疗价值。本综述全面概述TRPV1的多重功能,旨在为未来研究提供思路,并推动以TRPV1为靶点的新疗法研发,从而助力提升人类健康水平。

关键词组:瞬时受体电位香草酸亚型1(TRPV1);结构;门控机制;治疗靶点


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DOI:

10.1631/jzus.A2500209

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On-line Access:

2026-01-12

Received:

2025-05-25

Revision Accepted:

2025-07-06

Crosschecked:

2026-01-12

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