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Journal of Zhejiang University SCIENCE B

ISSN 1673-1581(Print), 1862-1783(Online), Monthly

A case report on indirect transmission of human rabies

Abstract: At present, virus infection is still a common threat to public health in developing countries. Human rabies remains a matter of great global concern with a case-fatality of almost 100%. The rabies virus belongs to the neurotropic type of virus of the Lyssavirus genus, and the disease presents as a deteriorating encephalomyelitis and is endemic throughout much of the world, particularly in Africa and Asia. Previous data have shown that, globally, approximately 59 000 human deaths are caused by rabies per year. Fortunately, human rabies can be treated through the timely administration of post-exposure prophylaxis (PEP). These days immunization using the rabies vaccine has become standard practice for individuals who have suffered bites or scratches from an animal, or who have been exposed to the body fluids of an infected animal. However, we have recently encountered a case of human rabies which arose through a rare transmission method, and we believe that lessons can and should be learnt from this incident.

Key words: Rabies,Communicable diseases,Virus,Vaccination

Chinese Summary  <25> 一例罕见的间接传播人狂犬病

概要:本文回顾性报告了一例较为罕见的间接传播人狂犬病患者的得病经过和救治过程,对其中的特殊之处进行分析和思考。本病例提供的一线临床实践资料,有助于提高对该疾病的认识以及制定更为科学、合理的狂犬病防治方案。该狂犬病患者无动物咬伤或接触动物体液等相关病史,而是通过其有少许皮损的拇指接触到被狗咬伤者的血液(可能被狗唾液污染)而感染狂犬病病毒,即间接的接触传播。因而,对于这类患者,临床上也应及时接种狂犬病疫苗或给予抗狂犬病免疫球蛋白。

关键词组:狂犬病;传染病;病毒;预防接种


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DOI:

10.1631/jzus.B1500109

CLC number:

R586

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On-line Access:

2015-11-04

Received:

2014-11-25

Revision Accepted:

2015-04-16

Crosschecked:

2015-10-21

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