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Journal of Zhejiang University SCIENCE B
ISSN 1673-1581(Print), 1862-1783(Online), Monthly
2025 Vol.26 No.6 P.527-545
Applications of bioactive peptides in cosmeceuticals: a review
Abstract: The cosmetic sector is a multibillion-dollar industry that requires constant attention being paid to innovative product development and engagement. Notably, its market value is projected to exceed 750 billion U.S. dollars by 2025, and it is expanding as novel, climate-friendly, green, and sustainable components from natural sources are incorporated. This review is written based on the numerous reports on the potential applications of food-derived peptides while focusing on their possible uses in the formulation of cosmeceutical and skincare products. First, the production methods of bioactive peptides linked to cosmeceutical uses are described. Then, we discuss the obtainment and characterization of different anti-inflammatory, antimicrobial, antioxidant, anti-aging, and other pleiotropic peptides with their specific mechanisms, from various food sources. The review concludes with salient considerations of the cost of production and pilot scale operation, stability, compatibility, user safety, site-specificity, and delivery methods, when designing or developing biopeptide-based cosmeceutical products.
Key words: Cosmetic; Skincare; Bioactive peptide; Functional ingredient; Cosmeceutical
1Institute for Global Health Innovations, Duy Tan University, Da Nang 550000, Vietnam
2Faculty of Medicine, Duy Tan University, Da Nang 550000, Vietnam
摘要:化妆品行业是一个价值数十亿美元的产业,需要持续聚焦于创新产品的开发以及市场参与度。值得注意的是,预计到2025年,其市场价值将超过7500亿美元,且随着天然来源的新颖、气候友好型、绿色及可持续的成分被纳入,该行业正在不断扩张。本综述基于众多有关食品源衍生肽潜在应用的报告而成,重点关注其在药妆和护肤品配方中的可能用途。首先,本文介绍了与药妆用途相关的生物活性肽的生产方法。随后,探讨了从各类食品来源获取并表征不同抗炎、抗菌、抗氧化、抗衰老和其他多效肽,及其特定机制。最后,重点阐述了在设计或开发基于生物肽的药妆产品时重点考虑的因素,包括生产成本、中试规模操作、稳定性、兼容性、用户安全性、位点特异性及递送方法等。
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DOI:
10.1631/jzus.B2400029
CLC number:
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On-line Access:
2025-06-25
Received:
2024-01-22
Revision Accepted:
2024-03-06
Crosschecked:
2025-06-25