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Journal of Zhejiang University SCIENCE A

ISSN 1673-565X(Print), 1862-1775(Online), Monthly

FACILE SYNTHESIS OF 4β-AMINOPODOPHYLLOTOXINS

Abstract: 4β-amino-4-desoxypodophyllotoxin and 4β-amino-4'-demethyl-4desoxypodophyllo-toxin were synthesized by reduction of the corresponding 4β-azidopodophyllotoxin derivatives with HCO2NH4/Pd-C in excellent yields under convenient and mild reactive condition.

Key words: podophyllotoxin, ammonium formate, synthesis


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DOI:

10.1631/jzus.2000.0027

CLC number:

O621

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Received:

1998-03-09

Revision Accepted:

1999-05-26

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