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Journal of Zhejiang University SCIENCE A
ISSN 1673-565X(Print), 1862-1775(Online), Monthly
2004 Vol.5 No.8 P.941-949
Study on properties of residue-residue contacts in protein
Abstract: Residue-residue contacts are very important in forming protein structure. In this work, we calculated the average probability of residue-residue contacts in 470 globular proteins and analyzed the distribution of contacts in the different interval of residues using Contacts of Structural Units (CSU) and Structural Classification (SCOP) software. It was found that the relationship between the average probability P̄L and the residue distance L for four structural classes of proteins could be expressed as lgPL=a+b×L, where a and b are coefficients. We also discussed the connection between two aspects of proteins which have equal array residue number and found that the distribution probability was stable (or unstable) if the proteins had the same (or different) compact (for example synthase) in the same structural class.
Key words: Globular protein, Structural class, Residue distance, Long- and short-range contact
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Open peer comments: Debate/Discuss/Question/Opinion
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DOI:
10.1631/jzus.2004.0941
CLC number:
O631
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2024-08-27
Received:
2023-10-17
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2024-05-08
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