Abstract: Environmental concerns have highlighted the need of cleaner technologies. A cleaner, convenient and selective technology has been developed for the preparation of 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol (DPMP) from 2-methyl-benzene-1,3-diol in water as solvent. The isolated yield of DPMP is up to 86% in good selectivity. The product structure was characterized by conventional methods, 1H-NMR and MS. This technology belongs to the modern concept of environmentally friendly low wastes or non-wastes technology (LWNWT).

Key words: Cleaner preparation, Greener technology, Selective synthesis, 2-methyl-benzene-1,3-diol, 3-(4,6-dimethoxy-pyrimidin-2-yloxy)-2-methyl-phenol

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