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Journal of Zhejiang University SCIENCE B

ISSN 1673-1581(Print), 1862-1783(Online), Monthly

Deep lingual arterial chemoembolization of tongue carcinoma with microcapsuled anticancer drug

Abstract: Objective: Microcapsule chemoembolism is a promising treatment of tumors. We describe a deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum. Methods: Lingual artery cast specimens from cadavers were microscopically examined, and 78 patients with tongue cancer were recruited and treated with the deep lingual arterial embolization therapy. Results: Microcapsule embolism occurred approximately at the fifth or sixth level of the deep lingual artery branches. The five-year survival rate was 88.5% (69 out of 78), and the ten-year survival rate 52.6% (41 out of 78). Conclusion: The deep lingual arterial embolization of tongue carcinoma with microcapsuled carboplatinum is an effective therapy to treat carcinoma in mid-margin or mid-body of the tongue.

Key words: Tongue carcinoma, Artery cast, Arterial chemoembolization, Deep lingual arterial embolization, Anticancer drug, Carboplatinum


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DOI:

10.1631/jzus.2007.B0704

CLC number:

R739.8

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On-line Access:

2024-08-27

Received:

2023-10-17

Revision Accepted:

2024-05-08

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