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Journal of Zhejiang University SCIENCE B

ISSN 1673-1581(Print), 1862-1783(Online), Monthly

2014 Vol.15 No.6 P.598-600

Hypocalcemia: a reversible cause of T wave alternans and heart failure

Yi-chen Yang, Fa-rong Shen, Yuan-qiang Lu

Department of Clinical Medicine, Graduate School, Zhejiang Chinese Medical University, Hangzhou 310053, China; Department of Emergency Medicine, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China

yangyichenyz@126.com, luyuanqiang201@gmail.com

Abstract: We have read with great interest the recent article “Cellular mechanism of cardiac alternans: an unresolved chicken or egg problem” by Zang and Xia (2014), published in Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology). The authors proposed that both calcium handling and electrical components of cardiac cells could be the cellular mechanism of cardiac alternans, and identifying the main mechanism of cardiac alternans could help to cure targeted patients with heart failure. Here, we present a particular case, which may help you to understand our viewpoint.

Key words: Hypocalcemia, Heart failure, Arrhythmias, Cardiac, Hypoparathyroidism

Chinese Summary  <31> 低钙血症：T波电交替和心衰的一个可逆病因

本文概要：由于钙离子在心肌细胞兴奋-收缩偶联中发挥着核心作用，低钙血症可诱发心肌病。临床上，由于低钙血症导致的T波电交替和急性心衰罕见，极易被忽视或误诊。研究显示，低钙血症引起的T波电交替和急性心衰往往是可逆的，因而及时纠正严重低钙血症十分重要。本文报告一例慢性甲状旁腺功能减退症患者，由于严重的低钙血症引起T波电交替和急性心衰发作，在迅速纠正低钙血症后，患者病情得以缓解，T波电交替完全消失，心功能部分恢复。通过复习该病例，有助于临床医生重视可引起T波电交替和心衰的可逆性因素-低钙血症。

关键词组：低钙血症；心力衰竭；心律失常；心性；甲状旁腺功能减退症


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DOI:

10.1631/jzus.B1400078

CLC number:

R541.7+6

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On-line Access:

2024-08-27

Received:

2023-10-17

Revision Accepted:

2024-05-08

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