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Journal of Zhejiang University SCIENCE B

ISSN 1673-1581(Print), 1862-1783(Online), Monthly

2018 Vol.19 No.9 P.735-738

Three-vessel coronary artery disease may predict changes in biochemical brain injury markers after off-pump coronary artery bypass grafting#

Wojciech Pawliszak, Krzysztof Szwed, Artur S?omka, Natalia Pieku?-S?omka, Magdalena Szwed, Mariusz Kowalewski, Ewa ?ekanowska, Alina Borkowska

Department of Cardiac Surgery, Nicolaus Copernicus University in Toru?, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland; Department of Clinical Neuropsychology, Nicolaus Copernicus University in Toru?, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland; Department of Pathophysiology, Nicolaus Copernicus University in Toru?, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland; Department of Inorganic and Analytical Chemistry, Nicolaus Copernicus University in Toru?, Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-635 Bydgoszcz, Poland; Clinical Department of Cardiac Surgery, Central Clinical Hospital of the Ministry of Interior in Warsaw, 02-507 Warsaw, Poland

artur.slomka@cm.umk.pl

Abstract: Neurological injury is a frequent and important complication of coronary artery bypass grafting (CABG). Several risk factors for this type of sequela have been identified, among them aortic arch atherosclerosis. Our previous study indicated that atherosclerotic burden in coronary arteries may likewise predict postoperative neurological complications (Pawliszak et al., 2016b). We assessed the severity of this condition by using the SYNTAX score calculator. However, diagnosing angiographic three-vessel coronary artery disease (3VD) could be an even simpler method of achieving this goal.

Key words: Cardiac surgery; Coronary artery disease; Glial fibrillary acidic protein; Neuroserpin; Phosphorylated axonal neurofilament subunit H

Chinese Summary  <17> 三支冠脉病变可预测非体外循环下冠状动脉旁路移植手术后颅脑损伤生化标志物的变化

关键词组：三支冠脉病变;磷酸化轴突神经丝亚基H;胶质纤维酸性蛋白;神经源性丝氨酸蛋白酶抑制素;血管造影诊断


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DOI:

10.1631/jzus.B1700553

CLC number:

R541.4

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On-line Access:

2018-09-04

Received:

2017-11-08

Revision Accepted:

2018-04-25

Crosschecked:

2018-08-07

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