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Journal of Zhejiang University SCIENCE B
ISSN 1673-1581(Print), 1862-1783(Online), Monthly
2019 Vol.20 No.11 P.928-932
Integrated analysis of hypoxia-induced miR-210 signature as a potential prognostic biomarker of hepatocellular carcinoma: a study based on The Cancer Genome Atlas
Abstract: Hepatocellular carcinoma (HCC) is one of the most common types of liver cancer and is the second leading cause of cancer mortality with an estimated 745 500 deaths annually (Jemal et al., 2011). Although new therapeutic modalities including novel chemotherapeutic interventions and targeted therapy have been applied, the prognosis of HCC patients remains unsatisfactory due to the high incidence of intrahepatic and distal metastases (Siegel et al., 2018).
Key words: miR-210; The Cancer Genome Atlas (TCGA); Hepatocellular carcinoma (HCC); Hypoxia; prognostic biomarker
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DOI:
10.1631/jzus.B1900343
CLC number:
R735.7
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On-line Access:
2019-10-09
Received:
2019-07-03
Revision Accepted:
2019-09-12
Crosschecked:
2019-09-12