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Bio-Design and Manufacturing  2022 Vol.5 No.1 P.153-162

http://doi.org/10.1007/s42242-021-00143-6


Preparation of conductive and transparent dipeptide hydrogels for wearable biosensor


Author(s):  Yafeng Jing, Anhe Wang, Jieling Li, Qi Li, Qingquan Han, Xuefang Zheng, Hongyu Cao & Shuo Bai

Affiliation(s):  College of Life Science and Biotechnology, Dalian University, Dalian, 116622, China; more

Corresponding email(s):   ahwang@ipe.ac.cn, caohongyu@foxmail.com, baishuo@ipe.ac.cn

Key Words:  Conductivity, Transparency, Peptide hydrogel, Polypyrrole-polydopamine nanoparticles, Wearable biosensor


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Yafeng Jing, Anhe Wang, Jieling Li, Qi Li, Qingquan Han, Xuefang Zheng, Hongyu Cao & Shuo Bai. Preparation of conductive and transparent dipeptide hydrogels for wearable biosensor[J]. Journal of Zhejiang University Science D, 2022, 5(1): 153-162.

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author="Yafeng Jing, Anhe Wang, Jieling Li, Qi Li, Qingquan Han, Xuefang Zheng, Hongyu Cao & Shuo Bai",
journal="Journal of Zhejiang University Science D",
volume="5",
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pages="153-162",
year="2022",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-021-00143-6"
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DOI - 10.1007/s42242-021-00143-6


Abstract: 
Conductive and transparent dipeptide hydrogels are desirable building blocks to prepare soft electronic devices and wearable biosensors due to their excellent biocompatibility, multi-functionality, and physiochemical properties similar to those of body tissues. However, the preparation of such hydrogels featuring high conductivity and transparency is a huge challenge because of the hydrophobic feature of conductive additives making the doping process difficult. To overcome this issue, hydrophilic conductive polydopamine (PDA)-doped polypyrrole (PPy) nanoparticles are introduced into the dipeptide hydrogel networks to form conductive nanofibrils in situ to achieve a good level of hydrophilic templating of the hydrogel networks. This technique creates a complete conductive network and allows visible light to pass through. The strategy proposed herein not only endows the dipeptide hydrogel with good conductivity and high transparency, but also provides a great potential application of conductive dipeptide hydrogels for body-adhered signal detection, as evidenced by the experimental data.

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