CLC number: TN911.73
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 0000-00-00
Cited: 2
Clicked: 5835
WANG Li-qiang, NI Xu-xiang, LU Zu-kang, ZHENG Xu-feng, LI Ying-sheng. Enhancing the quality metric of protein microarray image[J]. Journal of Zhejiang University Science A, 2004, 5(12): 1621-1628.
@article{title="Enhancing the quality metric of protein microarray image",
author="WANG Li-qiang, NI Xu-xiang, LU Zu-kang, ZHENG Xu-feng, LI Ying-sheng",
journal="Journal of Zhejiang University Science A",
volume="5",
number="12",
pages="1621-1628",
year="2004",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2004.1621"
}
%0 Journal Article
%T Enhancing the quality metric of protein microarray image
%A WANG Li-qiang
%A NI Xu-xiang
%A LU Zu-kang
%A ZHENG Xu-feng
%A LI Ying-sheng
%J Journal of Zhejiang University SCIENCE A
%V 5
%N 12
%P 1621-1628
%@ 1869-1951
%D 2004
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2004.1621
TY - JOUR
T1 - Enhancing the quality metric of protein microarray image
A1 - WANG Li-qiang
A1 - NI Xu-xiang
A1 - LU Zu-kang
A1 - ZHENG Xu-feng
A1 - LI Ying-sheng
J0 - Journal of Zhejiang University Science A
VL - 5
IS - 12
SP - 1621
EP - 1628
%@ 1869-1951
Y1 - 2004
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2004.1621
Abstract: The novel method of improving the quality metric of protein microarray image presented in this paper reduces impulse noise by using an adaptive median filter that employs the switching scheme based on local statistics characters; and achieves the impulse detection by using the difference between the standard deviation of the pixels within the filter window and the current pixel of concern. It also uses a top-hat filter to correct the background variation. In order to decrease time consumption, the top-hat filter core is cross structure. The experimental results showed that, for a protein microarray image contaminated by impulse noise and with slow background variation, the new method can significantly increase the sig-nal-to-noise ratio, correct the trends in the background, and enhance the flatness of the background, the consistency of the signal intensity.
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