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CLC number: R781.7+2

On-line Access: 2013-03-06

Received: 2012-03-10

Revision Accepted: 2012-10-30

Crosschecked: 2013-02-01

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Journal of Zhejiang University SCIENCE B 2013 Vol.14 No.3 P.253-258


Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach

Author(s):  Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao

Affiliation(s):  Department of Stomatology, Children’s Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s):   ruanwh1@sohu.com

Key Words:  Juvenile recurrent parotitis, Therapy, Pediatrics, Traditional Chinese medicine, Prospective study

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Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao. Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach[J]. Journal of Zhejiang University Science B, 2013, 14(3): 253-258.

@article{title="Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach",
author="Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach
%A Wen-hua Ruan
%A Mei-li Huang
%A Xiao-lei He
%A Feng Zhang
%A Hai-biao Tao
%J Journal of Zhejiang University SCIENCE B
%V 14
%N 3
%P 253-258
%@ 1673-1581
%D 2013
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1200072

T1 - Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach
A1 - Wen-hua Ruan
A1 - Mei-li Huang
A1 - Xiao-lei He
A1 - Feng Zhang
A1 - Hai-biao Tao
J0 - Journal of Zhejiang University Science B
VL - 14
IS - 3
SP - 253
EP - 258
%@ 1673-1581
Y1 - 2013
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1200072

Objective: To evaluate the pharmacological effects of traditional Chinese medicine, bear bile capsule and Huangqi granule, on recurrent parotitis in children. Methods: In this prospective, controlled, and randomized study, a total of 151 young children were divided into three groups: Group A included massaging the children’s parotid region and melting vitamin C in their mouth daily; Group B included swallowing bear bile capsule and Huangqi granule daily; and Group C included massages and vitamin C as prescribed in Group A, and traditional Chinese medicine as prescribed in Group B. Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years. Analysis of variance (ANOVA) and Ridit analysis were employed for statistical analysis. Results: The recurrence rate decreased in every group, but was significantly more in Groups B and C when compared to Group A. The recurrences significantly decreased (P<0.01) in Group B and their recovery rate was as high as 63%, significantly better than those of the other groups (P<0.01). Conclusions: Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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