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Pierre Duez


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Journal of Zhejiang University SCIENCE B 2017 Vol.18 No.3 P.194-214


Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents

Author(s):  Mlanie Poivre, Pierre Duez

Affiliation(s):  Unit of Therapeutic Chemistry and Pharmacognosy, Faculty of Medicine and Pharmacy, Research Institute for Health Sciences and Technology, University of MonsUMONS, Mons, Belgium

Corresponding email(s):   pierre.duez@umons.ac.be

Key Words:  Magnolia bark, Houpo, Chinese herb, Traditional Chinese medicine

Mlanie Poivre, Pierre Duez. Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents[J]. Journal of Zhejiang University Science B, 2017, 18(3): 194-214.

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author="Mlanie Poivre, Pierre Duez",
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T1 - Biological activity and toxicity of the Chinese herb Magnolia officinalis Rehder & E. Wilson (Houpo) and its constituents
A1 - Mlanie Poivre
A1 - Pierre Duez
J0 - Journal of Zhejiang University Science B
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B1600299

Traditional chinese herbal drugs have been used for thousands of years in Chinese pharmacopoeia. The bark of Magnolia officinalis Rehder & E. Wilson, known under the pinyin name “houpo”, has been traditionally used in Chinese and Japanese medicines for the treatment of anxiety, asthma, depression, gastrointestinal disorders, headache, and more. Moreover, Magnolia bark extract is a major constituent of currently marketed dietary supplements and cosmetic products. Much pharmacological activity has been reported for this herb and its major compounds, notably antioxidant, anti-inflammatory, antibiotic and antispasmodic effects. However, the mechanisms underlying this have not been elucidated and only a very few clinical trials have been published. In vitro and in vivo toxicity studies have also been published and indicate some intriguing features. The present review aims to summarize the literature on M. officinalis bark composition, utilisation, pharmacology, and safety.



Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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