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CLC number: R783

On-line Access: 2018-07-04

Received: 2016-11-13

Revision Accepted: 2017-07-23

Crosschecked: 2018-06-06

Cited: 0

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Citations:  Bibtex RefMan EndNote GB/T7714


Christian Mehl


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Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.7 P.525-534


Effect of ultraviolet photofunctionalization of dental titanium implants on osseointegration

Author(s):  Christian Mehl, Matthias Kern, Friederike Neumann, Telse Bähr, Jörg Wiltfang, Volker Gassling

Affiliation(s):  Department of Prosthodontics, Propaedeutics and Dental Materials, Christian-Albrechts University at Kiel, Arnold-Heller-Straße 16, 24105, Kiel, Germany; more

Corresponding email(s):   Christian.Mehl@HarderMehl.de

Key Words:  Dental implant, Osseointegration, Photofunctionalization

Christian Mehl, Matthias Kern, Friederike Neumann, Telse Bähr, Jörg Wiltfang, Volker Gassling. Effect of ultraviolet photofunctionalization of dental titanium implants on osseointegration[J]. Journal of Zhejiang University Science B, 2018, 19(7): 525-534.

@article{title="Effect of ultraviolet photofunctionalization of dental titanium implants on osseointegration",
author="Christian Mehl, Matthias Kern, Friederike Neumann, Telse Bähr, Jörg Wiltfang, Volker Gassling",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Effect of ultraviolet photofunctionalization of dental titanium implants on osseointegration
%A Christian Mehl
%A Matthias Kern
%A Friederike Neumann
%A Telse Bähr
%A Jörg Wiltfang
%A Volker Gassling
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 7
%P 525-534
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1600505

T1 - Effect of ultraviolet photofunctionalization of dental titanium implants on osseointegration
A1 - Christian Mehl
A1 - Matthias Kern
A1 - Friederike Neumann
A1 - Telse Bähr
A1 - Jörg Wiltfang
A1 - Volker Gassling
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 7
SP - 525
EP - 534
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1600505

Objective: The aim of the current study was to evaluate the effect of ultraviolet (UV) photofunctionalization of dental titanium implants with exposure to the oral cavity on osseointegration in an animal model. Methods: Forty-eight titanium implants (Camlog® Conelog® 4.3 mmx9.0 mm) were placed epicrestally into the edentulous jaws of three minipigs and implant stability was assessed by measuring the implant stability quotient (ISQ). Prior to implantation half of the implants were photofunctionalized with intense UV-light. After three months, the implants were exposed and ISQ was measured again. After six months of implant exposure, the minipigs were sacrificed and the harvested specimens were analyzed using histomorphometric, light, and fluorescence microscopy. Main results: Forty-two of 48 implants osseointegrated. The overall mean bone-implant contact area (BIC) was (64±22)%. No significant differences were found in BIC or ISQ value (multivariate analysis of variance (MANOVA), P>0.05) between implants with and without exposure to UV photofunctionalization. Conclusions: No significant effects were observed on osseointegration of dental titanium implants nine months after exposure of UV photofunctionalization.


方法:在三只小型猪的无牙颌中植入共48个钛种植体 (Camlog® Conelog® 4.3 mm×9.0 mm),测量其植体稳定度数值(ISQ).在植入手术前,用强紫外光对一半的种植体进行光化处理.植入手术三个月后,暴露种植体,再次测量ISQ.在暴露种植体六个月后,处死动物,通过组织形态学、光学和荧光显微镜对采样标本进行分析.


Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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