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On-line Access: 2018-09-30

Received: 2017-09-19

Revision Accepted: 2017-11-26

Crosschecked: 2018-09-10

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Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.10 P.776-784


Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens

Author(s):  Bin Li, Jin-Qiu Zhang, Xian-Gan Han, Zheng-Lei Wang, Yuan-Yuan Xu, Jin-Feng Miao

Affiliation(s):  Key Laboratory of Animal Physiology and Biochemistry, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China; more

Corresponding email(s):   xuyuanyuan@njau.edu.cn

Key Words:  Chlortetracycline, Macleaya cordata, Broiler chicken, Growth promotion, Gut flora

Bin Li, Jin-Qiu Zhang, Xian-Gan Han, Zheng-Lei Wang, Yuan-Yuan Xu, Jin-Feng Miao. Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens[J]. Journal of Zhejiang University Science B, 2018, 19(10): 776-784.

@article{title="Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens",
author="Bin Li, Jin-Qiu Zhang, Xian-Gan Han, Zheng-Lei Wang, Yuan-Yuan Xu, Jin-Feng Miao",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens
%A Bin Li
%A Jin-Qiu Zhang
%A Xian-Gan Han
%A Zheng-Lei Wang
%A Yuan-Yuan Xu
%A Jin-Feng Miao
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 10
%P 776-784
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1700435

T1 - Macleaya cordata helps improve the growth-promoting effect of chlortetracycline on broiler chickens
A1 - Bin Li
A1 - Jin-Qiu Zhang
A1 - Xian-Gan Han
A1 - Zheng-Lei Wang
A1 - Yuan-Yuan Xu
A1 - Jin-Feng Miao
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 10
SP - 776
EP - 784
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1700435

chlortetracycline (CTC), one kind of common antibiotic for prevention and treatment of various diseases, also exhibits good performance in accelerating the growth of livestock. Macleaya cordata, a traditional Chinese medicine, is usually used as a natural additive in livestock because of its anti-microbial, anti-fungal, anti-inflammatory, and pesticidal activity. In this work, we studied whether M. cordata helps regulate the growth-promoting effect of CTC on broiler chickens. It is demonstrated that M. cordata improves the growth-promoting effect of CTC on growth performance indices of broiler chickens, such as survival rate, daily weight, and feed to weight rate. M. cordata also delays the maximum of CTC residues in plasma. It may depend on the higher values of operational taxonomic unit (OTU) and the indices of α diversity driven by simultaneous use of CTC and M. cordata.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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[42]List of electronic supplementary materials

[43]Table S1 Mobile phase of HPLC-MS/MS

[44]Table S2 Chromatographic parameters of HPLC-MS/MS

[45]Table S3 Mass spectrometry parameters of HPLC-MS/MS

[46]Table S4 Mass spectrometry parameters of qualitative and quantitative ion pair in HPLC-MS/MS

[47]Fig. S1 Standard curve and peak figures

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