CLC number: Q189
On-line Access: 2019-06-06
Received: 2019-02-19
Revision Accepted: 2019-04-22
Crosschecked: 2019-05-27
Cited: 0
Clicked: 5995
Gao-Hang Wang, Li-Ming Wang. Recent advances in the neural regulation of feeding behavior in adult Drosophila[J]. Journal of Zhejiang University Science B, 2019, 20(7): 541-549.
@article{title="Recent advances in the neural regulation of feeding behavior in adult Drosophila",
author="Gao-Hang Wang, Li-Ming Wang",
journal="Journal of Zhejiang University Science B",
volume="20",
number="7",
pages="541-549",
year="2019",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1900080"
}
%0 Journal Article
%T Recent advances in the neural regulation of feeding behavior in adult Drosophila
%A Gao-Hang Wang
%A Li-Ming Wang
%J Journal of Zhejiang University SCIENCE B
%V 20
%N 7
%P 541-549
%@ 1673-1581
%D 2019
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1900080
TY - JOUR
T1 - Recent advances in the neural regulation of feeding behavior in adult Drosophila
A1 - Gao-Hang Wang
A1 - Li-Ming Wang
J0 - Journal of Zhejiang University Science B
VL - 20
IS - 7
SP - 541
EP - 549
%@ 1673-1581
Y1 - 2019
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1900080
Abstract: The ability to maintain metabolic homeostasis is a key capability critical for the survival and well-being of animals living in constantly changing environments. Metabolic homeostasis depends on neuromodulators, such as biogenic amines, neuropeptides, and hormones, to signal changes in animals’ internal metabolic status and to orchestrate their behaviors accordingly. An important example is the regulation of feeding behavior by conserved molecular and cellular mechanisms across the animal kingdom. Its relatively simple brain coupled with well-characterized genetics and behavioral paradigms makes the fruit fly Drosophila melanogaster an excellent model for investigating the neuromodulatory regulation of feeding behavior. In this review we discuss the neuromodulators and neural circuits that integrate the internal physiological status with external sensory cues and modulate feeding behavior in adult fruit flies. Studies show that various specific aspects of feeding behavior are subjected to unique neuromodulatory regulation, which permits fruit flies to maintain metabolic homeostasis effectively.
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