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On-line Access: 2021-12-14

Received: 2021-06-03

Revision Accepted: 2021-09-17

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Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Jue XIE

https://orcid.org/0000-0002-4270-671X

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Journal of Zhejiang University SCIENCE B 2021 Vol.22 No.12 P.1060-1064

http://doi.org/10.1631/jzus.B2100491


Factors associated with red blood cell transfusion among hospitalized patients: a cross-sectional study


Author(s):  Peiwen ZHANG, Dandan XU, Xinhan ZHANG, Mengyin WU, Xuecheng YAO, Dawei CUI, Jue XIE

Affiliation(s):  Department of Blood Transfusion, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China; more

Corresponding email(s):   zyyyxj2011@zju.edu.cn

Key Words:  Blood transfusion, Red blood cell, Triple exponential smoothing method


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Peiwen ZHANG, Dandan XU, Xinhan ZHANG, Mengyin WU, Xuecheng YAO, Dawei CUI, Jue XIE. Factors associated with red blood cell transfusion among hospitalized patients: a cross-sectional study[J]. Journal of Zhejiang University Science B, 2021, 22(12): 1060-1064.

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journal="Journal of Zhejiang University Science B",
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pages="1060-1064",
year="2021",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2100491"
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Abstract: 
red blood cell (RBC) transfusion is a clinically effective therapy in anemia, for example in patients with malignancies (Shander et al., 2020), bleeding (Odutayo et al., 2017), and preoperative anemia (Padmanabhan et al., 2019). The past few decades have witnessed a shortage of blood for transfusion due to limited health insurance coverage for blood use and the rapid expansion of hospitals (Chen et al., 2011; Shi et al., 2014). Blood donation levels may easily be affected by general changes in the environment, policy, major events such as disasters, and public sentiment (Hu et al., 2019). Meanwhile, the transfusion of allogeneic RBC is a double-edged sword, increasing the possibility of infectious and immunological complications, and also leading to higher morbidity and mortality after transfusion (Frank et al., 2012). Considering that the continual shortfall has been increasingly prominent, identifying the factors associated with RBC transfusion could help blood transfusion departments to improve their supply of blood products as well as their inventory management (O'Donnell et al., 2018).

住院患者红细胞输注量相关因素的横断面研究

概要:住院患者的红细胞输注量相关研究中,医院层面和患者层面的因素未得到充分认识。本研究从医院层面和患者层面这两个角度出发,将血液中心的供给量纳入考虑范畴,探讨影响患者红细胞输注数量的因素。我们从浙江大学医学院附属第一医院的医院信息系统中收集了从2013年1月至2020年12月期间病人红细胞的每日使用单位和相应的患者临床信息,基于每周红细胞总使用单位采用三重指数平滑法进行时间序列分析,并且以二元逻辑回归方法来追溯影响红细胞输注量的患者相关因素。研究结果表明,红细胞的给予单位数量与医院血液库存的季节性趋势和患者的整体状态有关。

关键词:输血;红细胞;三重指数平滑法;二元逻辑回归

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Reference

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[11]informationSupplementary

[12]Materials and methods; TablesS1‒S3; Fig. S1

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