CLC number:
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 0000-00-00
Cited: 0
Clicked: 673
Shixu DU, Leqin FANG, Yuanhui LI, Shuai LIU, Xue LUO, Shufei ZENG, Shuqiong ZHENG, Hangyi YANG, Yan XU, Dai LI, Bin ZHANG. Association between post-COVID-19 sleep disturbance and neurocognitive function: A comparative study based on propensity score matching[J]. Journal of Zhejiang University Science B, 1998, -1(-1): .
@article{title="Association between post-COVID-19 sleep disturbance and neurocognitive function: A comparative study based on propensity score matching",
author="Shixu DU, Leqin FANG, Yuanhui LI, Shuai LIU, Xue LUO, Shufei ZENG, Shuqiong ZHENG, Hangyi YANG, Yan XU, Dai LI, Bin ZHANG",
journal="Journal of Zhejiang University Science B",
volume="-1",
number="-1",
pages="",
year="1998",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2300831"
}
%0 Journal Article
%T Association between post-COVID-19 sleep disturbance and neurocognitive function: A comparative study based on propensity score matching
%A Shixu DU
%A Leqin FANG
%A Yuanhui LI
%A Shuai LIU
%A Xue LUO
%A Shufei ZENG
%A Shuqiong ZHENG
%A Hangyi YANG
%A Yan XU
%A Dai LI
%A Bin ZHANG
%J Journal of Zhejiang University SCIENCE B
%V -1
%N -1
%P
%@ 1673-1581
%D 1998
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2300831
TY - JOUR
T1 - Association between post-COVID-19 sleep disturbance and neurocognitive function: A comparative study based on propensity score matching
A1 - Shixu DU
A1 - Leqin FANG
A1 - Yuanhui LI
A1 - Shuai LIU
A1 - Xue LUO
A1 - Shufei ZENG
A1 - Shuqiong ZHENG
A1 - Hangyi YANG
A1 - Yan XU
A1 - Dai LI
A1 - Bin ZHANG
J0 - Journal of Zhejiang University Science B
VL - -1
IS - -1
SP -
EP -
%@ 1673-1581
Y1 - 1998
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2300831
Abstract: Despite that sleep disturbance and poor neurocognitive performance are common complaints among coronavirus disease 2019 (COVID-19) survivors, few studies have focused on the effect of post-COVID-19 sleep disturbance (PCSD) on cognitive function.This study aimed to identify the impact of PCSD on neurocognitive function and explore the associated risk factors for the worsening of this condition.This cross-sectional study was conducted via the web-based assessment in mainland China. neurocognitive function was evaluated by the modified online Integrated Cognitive Assessment (ICA) and the Number Ordering Test (NOT). Propensity score matching (PSM) was utilized to match the confounding factors between individuals with and without PCSD. Univariate analyses were performed to evaluate the effect of PCSD on neurocognitive function. The risk factors associated with worsened neurocognitive performance in PCSD individuals were explored using binary logistic regression.A total of 8692 individuals with COVID-19 diagnosis were selected for this study. Nearly half (48.80%) of the COVID-19 survivors reported sleep disturbance. After matching by PSM, a total of 3977 pairs (7954 individuals in total) were obtained. Univariate analyses revealed that PCSD was related to worse ICA and NOT performance (P<0.050). Underlying disease, upper respiratory infection, loss of smell or taste, severe pneumonia, and self-reported cognitive complaints were associated with worsened neurocognitive performance among PCSD individuals (p <0.050). Furthermore, aging, ethnicity (minority), and lower education level were found to be independent risk factors for worsened neurocognitive performance in PCSD individuals (P<0.050). PCSD was related to impaired neurocognitive performance. Therefore, appropriate prevention and intervention measures should be taken to minimize or prevent PCSD and eliminate its potential adverse effect on neurocognitive function.
Open peer comments: Debate/Discuss/Question/Opinion
<1>