JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

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Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach

Author(s): Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao
Affiliation(s): Department of Stomatology, Children�s Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; more
Corresponding email(s): ruanwh1@sohu.com
Key Words: Juvenile recurrent parotitis, Therapy, Pediatrics, Traditional Chinese medicine, Prospective study

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Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao. Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B1200072

@article{title="Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach",
author="Wen-hua Ruan, Mei-li Huang, Xiao-lei He, Feng Zhang, Hai-biao Tao",
journal="Journal of Zhejiang University Science B",
year="in press",
publisher="Zhejiang University Press & Springer",
doi="https://doi.org/10.1631/jzus.B1200072"
}

%0 Journal Article
%T Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach
%A Wen-hua Ruan
%A Mei-li Huang
%A Xiao-lei He
%A Feng Zhang
%A Hai-biao Tao
%J Journal of Zhejiang University SCIENCE B
%P 253-258
%@ 1673-1581
%D in press
%I Zhejiang University Press & Springer
doi="https://doi.org/10.1631/jzus.B1200072"

TY - JOUR
T1 - Effects of Huangqi and bear bile on recurrent parotitis in children: a new clinical approach
A1 - Wen-hua Ruan
A1 - Mei-li Huang
A1 - Xiao-lei He
A1 - Feng Zhang
A1 - Hai-biao Tao
J0 - Journal of Zhejiang University Science B
SP - 253
EP - 258
%@ 1673-1581
Y1 - in press
PB - Zhejiang University Press & Springer
ER -
doi="https://doi.org/10.1631/jzus.B1200072"

Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: Objective: To evaluate the pharmacological effects of traditional Chinese medicine, bear bile capsule and Huangqi granule, on recurrent parotitis in children. Methods: In this prospective, controlled, and randomized study, a total of 151 young children were divided into three groups: Group A included massaging the children’s parotid region and melting vitamin C in their mouth daily; Group B included swallowing bear bile capsule and Huangqi granule daily; and Group C included massages and vitamin C as prescribed in Group A, and traditional Chinese medicine as prescribed in Group B. Children were treated individually for one month and then a follow-up study was conducted for 1 to 3.5 years. Analysis of variance (ANOVA) and Ridit analysis were employed for statistical analysis. Results: The recurrence rate decreased in every group, but was significantly more in Groups B and C when compared to Group A. The recurrences significantly decreased (P<0.01) in Group B and their recovery rate was as high as 63%, significantly better than those of the other groups (P<0.01). Conclusions: Huangqi and bear bile could be a novel clinical approach for treating recurrent parotitis in children.

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