JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)

Neuroscientific therapies for subjective tinnitus

Author(s): Peng LIU¹, Xinmiao XUE², Zhixin ZHANG², Hanwen ZHOU², Cong XU¹, Lijun ZHANG¹, Zhen LI¹, Yongqing ZHOU¹, Shanwei SONG³, Yameng TIAN¹, Fangyuan WANG², Xiaoming LI¹, Shiming YANG²
Affiliation(s): ¹Department of Otolaryngology Head and Neck Surgery, Bethune International Peace Hospital, Shijiazhuang 050000, China; more
Corresponding email(s): fangyuanwang05@163.com, xmlmo@126.com, shm_yang@163.com
Key Words: Tinnitus; Neuromodulation; Magnetic stimulation; Electrical stimulation; Light stimulation

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Peng LIU¹, Xinmiao XUE², Zhixin ZHANG², Hanwen ZHOU², Cong XU¹, Lijun ZHANG¹, Zhen LI¹, Yongqing ZHOU¹, Shanwei SONG³, Yameng TIAN¹, Fangyuan WANG², Xiaoming LI¹, Shiming YANG². Neuroscientific therapies for subjective tinnitus[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2400579

@article{title="Neuroscientific therapies for subjective tinnitus",
author="Peng LIU¹, Xinmiao XUE², Zhixin ZHANG², Hanwen ZHOU², Cong XU¹, Lijun ZHANG¹, Zhen LI¹, Yongqing ZHOU¹, Shanwei SONG³, Yameng TIAN¹, Fangyuan WANG², Xiaoming LI¹, Shiming YANG²",
journal="Journal of Zhejiang University Science B",
year="in press",
publisher="Zhejiang University Press & Springer",
doi="https://doi.org/10.1631/jzus.B2400579"
}

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%T Neuroscientific therapies for subjective tinnitus
%A Peng LIU¹
%A Xinmiao XUE²
%A Zhixin ZHANG²
%A Hanwen ZHOU²
%A Cong XU¹
%A Lijun ZHANG¹
%A Zhen LI¹
%A Yongqing ZHOU¹
%A Shanwei SONG³
%A Yameng TIAN¹
%A Fangyuan WANG²
%A Xiaoming LI¹
%A Shiming YANG²
%J Journal of Zhejiang University SCIENCE B
%P
%@ 1673-1581
%D in press
%I Zhejiang University Press & Springer
doi="https://doi.org/10.1631/jzus.B2400579"

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T1 - Neuroscientific therapies for subjective tinnitus
A1 - Peng LIU¹
A1 - Xinmiao XUE²
A1 - Zhixin ZHANG²
A1 - Hanwen ZHOU²
A1 - Cong XU¹
A1 - Lijun ZHANG¹
A1 - Zhen LI¹
A1 - Yongqing ZHOU¹
A1 - Shanwei SONG³
A1 - Yameng TIAN¹
A1 - Fangyuan WANG²
A1 - Xiaoming LI¹
A1 - Shiming YANG²
J0 - Journal of Zhejiang University Science B
SP -
EP -
%@ 1673-1581
Y1 - in press
PB - Zhejiang University Press & Springer
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doi="https://doi.org/10.1631/jzus.B2400579"

Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: Tinnitus, a prevalent auditory symptom, can significantly impair quality of life, yet no definitive pharmacological interventions exist despite extensive ongoing research into its pathophysiology and treatments. The advent of biomedical engineering has introduced neuromodulation as a pivotal therapeutic approach alongside conventional strategies such as pharmacotherapy and surgery. Through the deployment of invasive and non-invasive techniques, using various modalities including magnetic, electronic, and optical means, neuromodulation aims to regulate neural functions. This has not only led to the refinement of fundamental theories but has also enhanced the optimization of clinical applications. As an emerging and promising intervention, neuromodulation enriches the toolkit available for basic neuroscience inquiry and broadens the spectrum of clinical therapies for conditions affecting the central nervous system, including tinnitus. In this paper, we succinctly review the current understanding of tinnitus mechanisms, discuss the features of diverse neuromodulation technologies, explore their application in tinnitus management, and contemplate future prospects for their development in treating tinnitus.

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