JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE B

Accepted manuscript available online (unedited version)

Small fish making a big difference: beloved star of environmental toxicology research in the current era

Author(s): Yang JIANG^1, ², Zhen SU², Jing ZHENG¹, Chih-Hung HSU¹, Ye CHEN^1, ²
Affiliation(s): ¹Department of Genetic and Metabolic Disease, The Children ’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China; more
Corresponding email(s): yechency@zju.edu.cn, ch_hsu@zju.edu.c
Key Words: Zebrafish model; Environmental toxicants; Environmental toxicology

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Yang JIANG^1,², Zhen SU², Jing ZHENG¹, Chih-Hung HSU¹, Ye CHEN^1,². Small fish making a big difference: beloved star of environmental toxicology research in the current era[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2500166

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Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: The zebrafish has emerged as a powerful model organism in life science owing to its remarkable biological characteristics and wide-ranging applications. This review provides a comprehensive overview of the recent advancements in research on zebrafish within the field of environmental toxicology, highlighting specific studies where this species was used to investigate various pollutants to elucidate their impacts and underlying mechanisms. The findings of these studies underscore the significant potential of zebrafish as a model to gain crucial insights into the ecological consequences of environmental contamination and toxicity pathways. By incorporating cutting-edge technologies such as artificial intelligence, high-throughput screening, and omics approaches, the use of zebrafish as a model organism is poised to significantly accelerate toxicological investigations, promote environmental conservation efforts, contribute to safeguarding human health, and advance sustainable development objectives.

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