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Ci SONG, Runsheng MA, Wei NI, Xinyue PENG, Xue LI, Ruoxi SHI, Yuanping ZHANG, Li YI. Pupillometry reveals hyper-arousal in response to auditory stimuli in autistic children[J]. Journal of Zhejiang University Science B,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.B2300462 @article{title="Pupillometry reveals hyper-arousal in response to auditory stimuli in autistic children", %0 Journal Article TY - JOUR
瞳孔测量揭示孤独症儿童对听觉刺激的过高唤醒反应1北京大学心理与认知科学学院, 中国北京市, 100871 2行为与心理健康北京市重点实验室, 中国北京市, 100871 3北京大学精神卫生研究所, 中国北京市, 100191 4卫生部精神卫生学重点实验室(北京大学), 中国北京市, 100191 5国家精神心理疾病临床医学研究中心(北京大学第六医院), 中国北京市, 100191 6青岛市自闭症研究会, 中国青岛市, 266107 7天津市宜童自闭症研究服务中心, 中国天津市, 300392 8北京大学IDG麦戈文脑科学研究所, 中国北京市, 100871 摘要:异常的感官反应在孤独症个体中被广泛报道,且与更多的功能困难有关。动态地看,他们对重复出现的感官刺激的反应平均值异常的背后因素可能是异常的首次反应和/或习惯化速率。本研究旨在使用瞳孔测量法测量不同类型听觉刺激引起的孤独症儿童的唤醒水平以及他们异常唤醒水平的动态变化。在实验一中,43名孤独症儿童和49名典型发展儿童被动地听重复出现的温和声音和负向声音。在实验二中,参加过实验一的39名孤独症儿童和44名典型发展儿童听按随机顺序出现的逐渐出现的无惊跳声音和突然出现的惊跳声音。研究发现,孤独症组在听负向声音和惊跳声音时瞳孔面积变化过大,这表明他们出现过高唤醒,而这些孤独症儿童在听温和声音和无惊跳声音时的唤醒水平正常。动态地看,在听负向声音时,孤独症组在首次反应中瞳孔面积变化的最大值过大,而该组的习惯化速率是正常的。总之,上述结果表明,负向和惊跳刺激可使孤独症儿童产生过高唤醒,且过高的首次反应在孤独症的过高唤醒中起到作用。因此,我们建议尽量减少负向和惊跳感官刺激或逐渐增加负向听觉刺激的音量来让孤独症儿童通过习惯化适应,从而降低他们的唤醒水平并减少问题行为。 关键词组: Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article
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