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Prospects for 3D bioprinting of organoids
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Preety Rawal, Dinesh M. Tripathi, Seeram Ramakrishna & Savneet Kaur. Prospects for 3D bioprinting of organoids[J]. Journal of Zhejiang University Science D, 2021, 4(3): 627-640.
@article{title="Prospects for 3D bioprinting of organoids",
author="Preety Rawal, Dinesh M. Tripathi, Seeram Ramakrishna & Savneet Kaur",
journal="Journal of Zhejiang University Science D",
volume="4",
number="3",
pages="627-640",
year="2021",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-020-00124-1"
}
%0 Journal Article
%T Prospects for 3D bioprinting of organoids
%A Preety Rawal
%A Dinesh M. Tripathi
%A Seeram Ramakrishna & Savneet Kaur
%J Journal of Zhejiang University SCIENCE D
%V 4
%N 3
%P 627-640
%@ 1869-1951
%D 2021
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-020-00124-1
TY - JOUR
T1 - Prospects for 3D bioprinting of organoids
A1 - Preety Rawal
A1 - Dinesh M. Tripathi
A1 - Seeram Ramakrishna & Savneet Kaur
J0 - Journal of Zhejiang University Science D
VL - 4
IS - 3
SP - 627
EP - 640
%@ 1869-1951
Y1 - 2021
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-020-00124-1
Abstract: Three-dimensional (3D) organoids derived from pluripotent or adult tissue stem cells seem to possess excellent potential for studying development and disease mechanisms alongside having a myriad of applications in regenerative therapies. However, lack of precise architectures and large-scale tissue sizes are some of the key limitations of current organoid technologies. 3D bioprinting of organoids has recently emerged to address some of these impediments. In this review, we discuss 3D bioprinting with respect to the use of bioinks and bioprinting methods and highlight recent studies that have shown success in bioprinting of stem cells and organoids. We also summarize the use of several vascularization strategies for the bioprinted organoids, that are critical for a complex tissue organization. To fully realize the translational applications of organoids in disease modeling and regenerative medicine, these areas in 3D bioprinting need to be appropriately harnessed and channelized.
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