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Bio-Design and Manufacturing  2024 Vol.7 No.5 P.819-822

http://doi.org/10.1007/s42242-024-00307-0


Evaluation of large language models for the classification of medical device software


Author(s):  Yu Han, Aaron Ceross, Florence Bourgeois, Paulo Savaget & Jeroen H. M. Bergmann

Affiliation(s):  Department of Engineering Science, University of Oxford, Old Road Campus, Oxford OX3 7QD, UK; more

Corresponding email(s):   jeroen.bergmann@eng.ox.ac.uk, yu.han@eng.ox.ac.uk, aaron.ceross@eng.ox.ac.uk, florence.bourgeois@childrens.harvard.edu, Paulo.Savaget@eng.ox.ac.uk

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Yu Han, Aaron Ceross, Florence Bourgeois, Paulo Savaget & Jeroen H. M. Bergmann. Evaluation of large language models for the classification of medical device software[J]. Journal of Zhejiang University Science D, 2024, 7(5): 819-822.

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author="Yu Han, Aaron Ceross, Florence Bourgeois, Paulo Savaget & Jeroen H. M. Bergmann",
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Abstract: 

上海大学刘媛媛教授等 | 细胞球构建策略及其在生物3D打印中的应用

本综述论文聚焦于细胞球制造及细胞球生物3D打印的最新发展趋势和相关研究进展。细胞是构建组织的基本单元。与传统二维培养细胞相比,细胞球是三维(3D)结构,可以自然地形成复杂的细胞-细胞和细胞-基质相互作用。这种结构更接近于生物体内细胞的自然环境。细胞球除了应用于疾病建模和药物筛选外,在组织再生方面也拥有巨大潜力。3D生物打印是一种先进的生物制造方法。它可以准确地将生物墨水沉积到预先设计的三维形状中,以创建复杂的生物组织。生物打印虽然是一种高效的手段,但要使细胞最终形成到复杂组织结构所需的时间较长。细胞球3D打印通过打印高细胞密度的细胞球,在后期培养时大幅缩短发育成大组织/器官的时间。将球体制造与生物打印技术结合,有望为再生医学领域的一系列难题提供全新解决路径。文章在介绍细胞球作为构建块的基础上,系统阐述和分析细胞球制造方法和细胞球3D生物打印的策略。

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