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Abstract: We herein present a case of carcinosarcoma arising as a primary lesion in the spleen with the presence of local invasion of chest wall prior to widespread metastasis all over the body of a female aged 64 years. The detailed information of therapy and imaging evidences of morphology, histology, and immunohistochemistry are fully provided. To the best of our knowledge, this is the fifth reported case of a primary splenic carcinosarcoma and even the first case to be described with local invasion in the mongoloid. carcinosarcoma that develops in the spleen with local invasion is extremely rare.

一例脾脏原发性肉瘤侵犯胸壁的病例报道

[1]Booth, C., Zahn, C.M., McBroom, J., et al., 2004. Retroperitoneal müllerian carcinosarcoma associated with endometriosis: a case report. Gynecol. Oncol., 93(2):546-549.

[2]Cass, I., Resnik, E., Chambers, J.T., et al., 1996. Combination chemotherapy with etoposide, cisplatin, and doxorubicin in mixed müllerian tumors of the adnexa. Gynecol. Oncol., 61(3):309-314.

[3]Chmiel, B., Wodolazski, A., Kozaczka, A., 2005. Carcinosarcoma of the pancreas—case report and literature review. Wiad. Lek., 58(3-4):243-246 (in Polish).

[4]Cicin, I., Saip, P., Eralp, Y., et al., 2008. Ovarian carcinosarcomas: clinicopathological prognostic factors and evaluation of chemotherapy regimens containing platinum. Gynecol. Oncol., 108(1):136-140.

[5]Cornette, J., Tjalma, W.A., Buytaert, P., 2005. Biphasic sarcomatoid carcinoma or carcinosarcoma of the breast: prognosis and therapy. Eur. J. Gynaecol. Oncol., 26(5):514-516.

[6]Darvishian, F., Sullivan, J., Teichberg, S., et al., 2002. Carcinosarcoma of the pancreas: a case report and review of the literature. Arch. Pathol. Lab. Med., 126(9):1114-1117.

[7]Dave, K.S., Chauhan, A., Bhansali, R., et al., 2011. Uterine carcinosarcomas: 8-year single center experience of 25 cases. Indian J. Med. Paediatr. Oncol., 32(3):149-153.

[8]di Vizio, D., Insabato, L., Conzo, G., et al., 2001. Sarcomatoid carcinoma of the colon: a case report with literature review. Tumori, 87(6):431-435.

[9]Gadducci, A., Romanini, A., 2001. Adjuvant chemotherapy in early stage uterine sarcomas: an open question. Eur. J. Gynaecol. Oncol., 22(5):352-357.

[10]Galaal, K., Kew, F.M., Tam, K.F., et al., 2009. Evaluation of prognostic factors and treatment outcomes in uterine carcinosarcoma. Eur. J. Obstet. Gynecol. Reprod. Biol., 143(2):88-92.

[11]Iezzoni, J.C., Mills, S.E., 1993. Sarcomatoid carcinomas (carcinosarcomas) of the gastrointestinal tract: a review. Semin. Diagn. Pathol., 10(2):176-187.

[12]Isimbaldi, G., Sironi, M., Assi, A., 1996. Sarcomatoid carcinoma of the colon: report of the second case with immunohistochemical study. Pathol. Res. Pract., 192(5):483-487.

[13]Joy, E.R., Cornish, J.A., Bootun, R., et al., 2012. Primary carcinosarcoma of the spleen. J. Surg. Case Rep., 2012(7):3.

[14]Kanthan, R., Senger, J.L., 2011. Uterine carcinosarcomas (malignant mixed Müllerian tumours): a review with special emphasis on the controversies in management. Obstet. Gynecol. Int., 2011:470795.

[15]Ko, M.L., Jeng, C.J., Huang, S.H., et al., 2005. Primary peritoneal carcinosarcoma (malignant mixed mullerian tumor): report of a case with five-year disease free survival after surgery and chemoradiation and a review of literature. Acta Oncol., 44(7):756-760.

[16]Kochar, K., Vijayasekar, C., Pandey, U., et al., 2009. Primary carcinosarcoma of the spleen: case report of a rare tumor and review of the literature. Int. J. Surg. Pathol., 17(1):72-77.

[17]Morinaga, S., Ohyama, R., Koizumi, J., 1992. Low-grade mucinous cystadenocarcinoma in the spleen. Am. J. Surg. Pathol., 16(9):903-908.

[18]Park, H.J., Kim, H.J., Wu, H.G., et al., 2011. The influence of adjuvant radiotherapy on patterns of failure and survivals in uterine carcinosarcoma. Radiation Oncol. J., 29(4):228-235.

[19]Rao, A., Mathew, G., Marimuthu, K., et al., 2007. Carcinosarcoma of the spleen: literature review of a very rare tumour. Open Med., 2(2):230-235.

[20]Resnik, E., Chambers, S.K., Carcangiu, M.L., et al., 1995. A phase II study of etoposide, cisplatin, and doxorubicin chemotherapy in mixed Müllerian tumors (MMT) of the uterus. Gynecol. Oncol., 56(3):370-375.

[21]Steeper, T.A., Piscioli, F., Rosai, J., 1983. Squamous cell carcinoma with sarcoma-like stroma of the female genital tract. Clinicopathologic study of four cases. Cancer, 52(5):890-898.

[22]Thompson, L., Chang, B., Barsky, S.H., 1996. Monoclonal origins of malignant mixed tumors (carcinosarcomas): evidence for a divergent histogenesis. Am. J. Surg. Pathol., 20(3):277-285.

[23]Westra, W.H., Anderson, B.O., Klimstra, D.S., 1994. Carcinosarcoma of the spleen: an extragenital malignant mixed müllerian tumor? Am. J. Surg. Pathol., 18(3):309-315.

[24]Yan, J.F., Kuang, T.T., Ji, D.Y., et al., 2015. Laparoscopic versus open distal pancreatectomy for benign or premalignant pancreatic neoplasms: a two-center comparative study. J. Zhejiang Univ.-Sci. B (Biomed. & Biotechnol.), 16(7):573-579.