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Received: 2004-10-29

Revision Accepted: 2005-01-27

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Journal of Zhejiang University SCIENCE B 2005 Vol.6 No.5 P.408-412


Statistical properties of nucleotide clusters in DNA sequences

Author(s):  CHENG Jun, ZHANG Lin-xi

Affiliation(s):  Department of Physics, Jinhua University, Jinhua 321017, China; more

Corresponding email(s):   Jh_Chengjun@163.com

Key Words:  DNA sequence, Plasmodium falciparum 3D7, Nucleotide clusters, Power law

CHENG Jun, ZHANG Lin-xi. Statistical properties of nucleotide clusters in DNA sequences[J]. Journal of Zhejiang University Science B, 2005, 6(5): 408-412.

@article{title="Statistical properties of nucleotide clusters in DNA sequences",
author="CHENG Jun, ZHANG Lin-xi",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

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%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2005.B0408

T1 - Statistical properties of nucleotide clusters in DNA sequences
A1 - CHENG Jun
A1 - ZHANG Lin-xi
J0 - Journal of Zhejiang University Science B
VL - 6
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EP - 412
%@ 1673-1581
Y1 - 2005
PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2005.B0408

Using the complete genome of Plasmodium falciparum 3D7 which has 14 chromosomes as an example, we have examined the distribution functions for the amount of C or G and A or T consecutively and non-overlapping blocks of m bases in this system. The function P(S) about the number of the consecutive C-G or A-T content cluster conforms to the relation P(S)∝eαs; values of the scaling exponent αCG are much larger than αAT; and αAT of 14 chromosomes are hardly changed, whereas αCG of 14 chromosomes have a number of fluctuations. We found maximum value of A-T cluster size is much larger than C-G, which implies the existence of large A-T cluster. Our study of the width function ξ(m) of cluster C-G content showed that follows good power law ξ(m)∝mγ. The average γ̄ for 14 chromosomes is 0.931. These investigations provide some insight into the nucleotide clusters of DNA sequences, and help us understand other properties of DNA sequences.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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