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On-line Access: 2022-05-13

Received: 2021-12-13

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 ORCID:

Huayi LIU

https://orcid.org/0000-0002-7571-7335

Yijia MAO

https://orcid.org/0000-0002-3621-7485

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Journal of Zhejiang University SCIENCE B 2022 Vol.23 No.5 P.353-364

http://doi.org/10.1631/jzus.B2101055


Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor


Author(s):  Yijia MAO, Lingkai MENG, Huayi LIU, Yuting LU, Kuo YANG, Guangze OUYANG, Yanran BAN, Shuang CHEN

Affiliation(s):  Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301608, China; more

Corresponding email(s):   15900369830@163.com

Key Words:  Vascular endothelial growth factor (VEGF), VEGF receptor, Traditional Chinese medicine (TCM)


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Yijia MAO, Lingkai MENG, Huayi LIU, Yuting LU, Kuo YANG, Guangze OUYANG, Yanran BAN, Shuang CHEN. Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor[J]. Journal of Zhejiang University Science B, 2022, 23(5): 353-364.

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author="Yijia MAO, Lingkai MENG, Huayi LIU, Yuting LU, Kuo YANG, Guangze OUYANG, Yanran BAN, Shuang CHEN",
journal="Journal of Zhejiang University Science B",
volume="23",
number="5",
pages="353-364",
year="2022",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2101055"
}

%0 Journal Article
%T Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor
%A Yijia MAO
%A Lingkai MENG
%A Huayi LIU
%A Yuting LU
%A Kuo YANG
%A Guangze OUYANG
%A Yanran BAN
%A Shuang CHEN
%J Journal of Zhejiang University SCIENCE B
%V 23
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%D 2022
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B2101055

TY - JOUR
T1 - Therapeutic potential of traditional Chinese medicine for vascular endothelial growth factor
A1 - Yijia MAO
A1 - Lingkai MENG
A1 - Huayi LIU
A1 - Yuting LU
A1 - Kuo YANG
A1 - Guangze OUYANG
A1 - Yanran BAN
A1 - Shuang CHEN
J0 - Journal of Zhejiang University Science B
VL - 23
IS - 5
SP - 353
EP - 364
%@ 1673-1581
Y1 - 2022
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B2101055


Abstract: 
vascular endothelial growth factor (VEGF) is the main regulator of physiological angiogenesis during embryonic development, bone growth, and reproductive function, and it also participates in a series of pathological changes. traditional Chinese medicine (TCM), with a history of more than 2000 years, has been widely used in clinical practice, while the exploration of its mechanisms has only begun. This review summarizes the research of recent years on the influence of TCM on VEGF. It is found that many Chinese medicines and recipes have a regulatory effect on VEGF, indicating that Chinese medicine has broad prospects as a complementary and alternative therapy, providing new treatment ideas for clinical applications and the theoretical basis for research on the mechanisms of TCM.

中药对血管内皮生长因子的治疗潜力

概要:血管内皮生长因子是胚胎发育、骨骼生长、生殖功能等过程中生理性血管生成的共同调节因子,同时也参与一系列的病理变化。中医有2000多年的历史,在临床上得到了广泛的应用,但对中医机制的探索才刚刚开始。本文总结了近年来中医药干预血管内皮生长因子的相关研究,发现许多中药和方剂对血管内皮生长因子具有调节作用,说明中医药作为补充和替代疗法具有广阔的前景,为临床提供新的治疗思路,并为中医药的机制研究提供理论依据。

关键词:血管内皮生长因子;血管内皮生长因子受体;中医药

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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