JZUS - Journal of Zhejiang University SCIENCE

Journal of Zhejiang University SCIENCE A

Accepted manuscript available online (unedited version)

Mitigating pre-focal heating using a spherical Fibonacci lattice HIFU array and a near-field focusing strategy

Author(s): Xiongfei QU¹, Nan WU², Yazhu CHEN¹, Guofeng SHEN¹
Affiliation(s): ¹School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China ；²Shanghai Shende Green Medical Era Healthcare Technology Co., Ltd., Shanghai 200233, China
Corresponding email(s): shenguofeng@sjtu.edu.cn
Key Words: High-intensity focused ultrasound; Phased array; Element arrangement; Focus steering

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Xiongfei QU¹, Nan WU², Yazhu CHEN¹, Guofeng SHEN¹. Mitigating pre-focal heating using a spherical Fibonacci lattice HIFU array and a near-field focusing strategy[J]. Journal of Zhejiang University Science A,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.A2400192

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author="Xiongfei QU¹, Nan WU², Yazhu CHEN¹, Guofeng SHEN¹",
journal="Journal of Zhejiang University Science A",
year="in press",
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doi="https://doi.org/10.1631/jzus.A2400192"
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%T Mitigating pre-focal heating using a spherical Fibonacci lattice HIFU array and a near-field focusing strategy
%A Xiongfei QU¹
%A Nan WU²
%A Yazhu CHEN¹
%A Guofeng SHEN¹
%J Journal of Zhejiang University SCIENCE A
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doi="https://doi.org/10.1631/jzus.A2400192"

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T1 - Mitigating pre-focal heating using a spherical Fibonacci lattice HIFU array and a near-field focusing strategy
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A1 - Yazhu CHEN¹
A1 - Guofeng SHEN¹
J0 - Journal of Zhejiang University Science A
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Y1 - in press
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doi="https://doi.org/10.1631/jzus.A2400192"

Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: Focus steering technique plays a crucial role in various high-intensity focused ultrasound (HIFU) treatment scenarios. However, due to current technological limitations, the focus quality degrades rapidly and prefocal grating lobes arise with increasing focus-shifting distance, which may adversely affect the safety of the treatment. To enlarge the focal steering range of a phased array, a novel method for array element arrangement is proposed in this study, which can increase both the safety and efficient steering range of the focus. Additionally, a ″near-field focusing″ strategy for ablation using an HIFU phased array is introduced. Experimental results demonstrate that this strategy not only effectively reduces the average acoustic intensity at the medium's surface but also inhibits temperature elevation in the prefocal region.Thus, this approach could mitigate the risks of skin burn and abdominal edema during clinical HIFU therapy.

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