Abstract: In this study, an ultrasonic-assisted wet mineralization process was developed using ordinary Portland cement as the raw material. This approach was designed to advance the use of mineralization technologies in construction materials by simultaneously enhancing mechanical properties and mineralization efficiency. A comprehensive microstructural analysis was conducted to elucidate the underlying mineralization mechanisms facilitated by ultrasonic treatment. Furthermore, an industrial-scale implementation framework was developed to support the practical application of this technique. We found that the pH variation during the process followed three distinct stages: a rapid drop, a plateau, and a gradual decline. During the same wet mineralization period, the content of C-S-H in the ultrasonic-assisted cement suspension increased by 16%. Ultrasonic-assisted?treatment improved the degree of mineralization and suppressed the growth of large crystals. Moreover, the incorporation of wet mineralization-treated suspensions into cement pastes significantly increased the compressive strength of the cementitious system. The most notable enhancement was observed when ultrasonic-assisted wet mineralization was conducted for 15 min, which resulted in a 25.78% increase in 1-day compressive strength and a 12.19% improvement in 28-day compressive strength. A 25-min ultrasonic-assisted treatment gave the greatest reduction in setting time, shortening the initial setting time by 19.46% and the final setting time by 12.98%. Based on a calculated ultrasonic mineralization energy efficiency factor, we determined that the ultrasonic-assisted wet mineralization process achieved its highest efficiency within the first 5 minutes. Prolonged mineralization resulted in a noticeable decline in mineralization efficiency.