Journal of Zhejiang University

Journal of Zhejiang University SCIENCE A

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Implantable flexible neuroelectrodes: advances in material innovation, structural design, and performance optimization

Author(s): Jiaqi SU¹, Haomin WANG^1, ², Lu HAN¹, Rong CHENG¹, Runfang HAO^1, ², Shengbo SANG^1, ²
Affiliation(s): ¹Shanxi Key Laboratory of Artificial Intelligence & Micro Nano Sensors, College of Integrated Circuits, Taiyuan University of Technology, Taiyuan 030024, China ²Key Lab of Advanced Transducers and Intelligent Control System of the Ministry of Education, Taiyuan University of Technology, Taiyuan 030024, China
Corresponding email(s): Haomin WANG, wanghaomin@tyut.edu.cn Shengbo SANG, sunboa-sang@tyut.edu.cn
Key Words: Implantable; Neural microelectrodes; Electrode material; Electrode structure; Electrode key performance

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Jiaqi SU¹, Haomin WANG^1,², Lu HAN¹, Rong CHENG¹, Runfang HAO^1,², Shengbo SANG^1,². Implantable flexible neuroelectrodes: advances in material innovation, structural design, and performance optimization[J]. Journal of Zhejiang University Science A,in press.Frontiers of Information Technology & Electronic Engineering,in press.https://doi.org/10.1631/jzus.A2600114

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author="Jiaqi SU¹, Haomin WANG^1,², Lu HAN¹, Rong CHENG¹, Runfang HAO^1,², Shengbo SANG^1,²",
journal="Journal of Zhejiang University Science A",
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publisher="Zhejiang University Press & Springer",
doi="https://doi.org/10.1631/jzus.A2600114"
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Abstract
Chinese Summary
Academic Network
Reviewer Comment

Abstract: In recent years, implantable neuroelectrodes have been widely applied in various fields, including deep brain electrical stimulation, neuroprosthesis and recording neuronal electrical activity in neuroscience research. However, with the rapid advancement of neuroscience and brain-computer interface technology, the limitations of traditional rigid neural microelectrodes have become increasingly evident. Flexible neuroelectrodes constructed from soft materials are emerging as a key research focus in the neural interface field. This review presents a systematic classification of the material selection, structural design, and key performance of implantable flexible neuroelectrodes and analyzes the optimization of achieving electrode flexibility in avoiding tissue damage and immune response. Furthermore, we summarized the contemporary challenges in performance optimization and material innovation, proposing potential solutions. By integrating and reviewing existing innovative approaches to flexible implantable neuroelectrodes, this review aims to provide an important theoretical foundation and technical guidance for the development of high-performance implantable neuroelectrodes

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On-line Access: 2026-06-15

Received: 2026-02-26

Revision Accepted: 2026-05-08

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Cited: 0

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Citations: Bibtex RefMan EndNote GB/T7714

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