Abstract: The population genetic data and forensic parameters of 19 x-chromosome short tandem repeat (X-STR) loci in Chinese uygur ethnic minority are presented. These loci were detected in a sample of 233 (94 males and 139 females) unrelated healthy individuals. We observed 238 alleles at the 19 X-STR loci, with the corresponding gene frequencies spanning the range from 0.0021 to 0.5644. After Bonferroni correction (P>0.0026), there were no significant deviations from Hardy-Weinberg equilibrium. The cumulative power of discrimination in females and males, and the probability of exclusion of the 19 X-STR loci were 0.999 999 999 999 999 999 998 091, 0.999 999 999 999 966, and 0.999 999 986 35, respectively. The cumulative mean exclusion chance was 0.999 999 992 849 in deficiency cases, 0.999 999 999 999 628 in normal trios, and 0.999 999 998 722 in duo cases. The high value of the forensic parameters mentioned above revealed that the novel panel of 19 loci had important values for forensic applications in the uygur group.

新疆维吾尔族人群19个X-STR新组合基因座 遗传多态性研究

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[27]List of electronic supplementary materials

[28]Table S1 Haplotype diversities of seven clusters in Uygur male individuals (n=94)

[29]Table S2 Fst and P-values for allele frequency distribution between Uygur ethnic group and the other groups previously published