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Bio-Design and Manufacturing  2019 Vol.2 No.1 P.24-30

http://doi.org/10.1007/s42242-019-00034-x


One-dimensional microstructure-assisted intradermal and intracellular delivery


Author(s):  Wensen Jiang, Liang Ma, Xiaobin Xu

Affiliation(s):  Materials Science and Engineering SchoolTongji UniversityShanghaiChina; more

Corresponding email(s):   xiaobinxu@tongji.edu.cn

Key Words:  Biomedical devices, Intradermal, Intracellular, 1D nanostructure, Drug delivery


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Wensen Jiang, Liang Ma, Xiaobin Xu. One-dimensional microstructure-assisted intradermal and intracellular delivery[J]. Journal of Zhejiang University Science D, 2019, 2(1): 24-30.

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author="Wensen Jiang, Liang Ma, Xiaobin Xu",
journal="Journal of Zhejiang University Science D",
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year="2019",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-019-00034-x"
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Abstract: 
The advancement in the materials manufacturing at micrometer and nanometer scales has already enabled numerous applications in electronics, optics, chemistry, biology and medicine. biomedical devices carrying micro-/nanostructures are currently being widely used in drug delivery, drug release, biosensing and therapy. New clinical methods for disease diagnosis and treatments are being developed enabled by nanotechnology. One-dimensional (1D) structures are playing an important role in the direct drug delivery both in vivo and ex vivo among various micro-/nanostructures. Here, in this paper, we reviewed recent progresses made on next-generation intradermal and intracellular delivery strategies and applications with focus on 1D microstructure-based approaches.

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