CLC number: TQ028.3
On-line Access: 2024-08-27
Received: 2023-10-17
Revision Accepted: 2024-05-08
Crosschecked: 0000-00-00
Cited: 4
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LÜ Yu-bin, YANG Yi-wen, WU Ping-dong. Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed[J]. Journal of Zhejiang University Science B, 2006, 7(7): 559-564.
@article{title="Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed",
author="LÜ Yu-bin, YANG Yi-wen, WU Ping-dong",
journal="Journal of Zhejiang University Science B",
volume="7",
number="7",
pages="559-564",
year="2006",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2006.B0559"
}
%0 Journal Article
%T Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed
%A LÜ
%A Yu-bin
%A YANG Yi-wen
%A WU Ping-dong
%J Journal of Zhejiang University SCIENCE B
%V 7
%N 7
%P 559-564
%@ 1673-1581
%D 2006
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2006.B0559
TY - JOUR
T1 - Separation of phosphatidylcholine from soybean phospholipids by simulated moving bed
A1 - LÜ
A1 - Yu-bin
A1 - YANG Yi-wen
A1 - WU Ping-dong
J0 - Journal of Zhejiang University Science B
VL - 7
IS - 7
SP - 559
EP - 564
%@ 1673-1581
Y1 - 2006
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2006.B0559
Abstract: A simulated moving bed (SMB), equipped with eight silica-gel columns, was used to separate phosphatidylcholine (PC) from soybean phospholipids. The effects of flow rate in Sections 2 (Q2) and 3 (Q3), switching time, feed flow rate and feed concentration on the operating performance parameters: purity, recovery, productivity and desorbent consumption were studied. Operating conditions leading to more than 90% purity in both outlet streams have been identified, together with those achieving optimal performance. Regions leading to complete separation are observed and explained theoretically. As the mass-transfer effect was not considered, the triangle theory only gives initial guesses for the optimal operating conditions.
[1] Amari, J.V., Brown, P.R., 1990. Isolation and purification of lecithin by preparative high-performance liquid chromatography. Journal of Chromatography A, 517(1):219-228.
[2] Bruce, P., 1998. Simulated moving bed processing: escape from the high-cost box. Journal of Chromatography A, 827:43-160.
[3] Jupke, A., Epping, A., Schmidt-Traub, H., 2002. Optimal design of batch and simulated moving bed chromatographic separation processes. Journal of Chromatography A, 944(1-2):93-117.
[4] Li, Y., 2004. A Study of Analysis and Purification of Soybean Phosphatidylcholine. Master Thesis, Zhejiang University, Hangzhou (in Chinese).
[5] Mazzotti, M., Storti, G., Morbidelli, M., 1997. Optimal operation of simulated moving bed units for nonlinear chromatographic separations. Journal of Chromatography A, 769(1):3-24.
[6] Meeren, P.V., Vanderdeelen, J., Huys, M., Baert, L., 1990. Optimization of the column load ability for the preparative HPLC separation of soybean phospholipids. JAOCS, 67:815-820.
[7] Migliorini, C., Mazzotti, M., Morbidelli, M., 1998. Continuous chromatographic separation through simulated moving beds under linear and nonlinear conditions. Journal of Chromatography A, 827(2):161-173.
[8] Ruthven, D.M., 1984. Principles of Adsorption and Adsorption Processes. Wiley, New York, p.380-409.
[9] Ruthven, D.M., Ching, C.B., 1989. Counter-current and simulated counter-current adsorption separation process. Chemical Engineering Science, 44(5):1011-1038.
[10] Storti, G., Mazzotti, M., Morbidelli, M., Carra, S., 1993. Robust design of binary countercurrent adsorption separation processes. AICHE J., 39(3):471-492.
Open peer comments: Debate/Discuss/Question/Opinion
<1>
Kevin Lopez@UNAM<kevinlopez\_qfb@hotmail.com>
2013-10-29 04:29:24
thanks for your help in my research