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On-line Access: 2019-04-15
Received: 2018-09-19
Revision Accepted: 2018-10-30
Crosschecked: 2019-03-14
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Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds
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Juqing Song, Guanglin Zhu, Huichang Gao, Lin Wang, Nanying Li, Xuetao Shi, Yingjun Wang. Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds[J]. Journal of Zhejiang University Science D, 2018, 1(4): 254-264.
@article{title="Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds",
author="Juqing Song, Guanglin Zhu, Huichang Gao, Lin Wang, Nanying Li, Xuetao Shi, Yingjun Wang",
journal="Journal of Zhejiang University Science D",
volume="1",
number="4",
pages="254-264",
year="2018",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-018-0027-9"
}
%0 Journal Article
%T Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds
%A Juqing Song
%A Guanglin Zhu
%A Huichang Gao
%A Lin Wang
%A Nanying Li
%A Xuetao Shi
%A Yingjun Wang
%J Journal of Zhejiang University SCIENCE D
%V 1
%N 4
%P 254-264
%@ 1869-1951
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-018-0027-9
TY - JOUR
T1 - Origami meets electrospinning: a new strategy for 3D nanofiber scaffolds
A1 - Juqing Song
A1 - Guanglin Zhu
A1 - Huichang Gao
A1 - Lin Wang
A1 - Nanying Li
A1 - Xuetao Shi
A1 - Yingjun Wang
J0 - Journal of Zhejiang University Science D
VL - 1
IS - 4
SP - 254
EP - 264
%@ 1869-1951
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-018-0027-9
Abstract: Inspired by the constitution of things in the natural world, three-dimensional (3D) nano?ber scaffold/cells complex was constructed via the combination of electrospinning technology and origami techniques. The nano?ber boxes prepared by origami provided a limited space for the layer-by-layer nano?ber ?lms, and the human fetal osteoblasts (hFOBs) seeded on the both sides of the nano?ber ?lms were expected to facilitate the bonding of the adjacent nano?ber ?lms through the secretion of extracellular matrix. Speci?cally, the hFOBs presented 3D distribution in the nano?ber scaffold, and they can stretch across the gaps between the adjacent nano?ber ?lms, forming the cell layers and ?lling the whole 3D nano?ber scaffold.Eventually,a3Dblockcomposedofelectrospunnano?berscaffoldandcellswasobtained,whichpossessespotential applications in bone tissue engineering. Interestingly, we also created 3D nano?ber structures that range from simple forms to intricate architectures via origami, indicating that the combination of electrospinning technology and origami techniques is a feasible method for the 3D construction of tissue engineering scaffolds.
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