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On-line Access: 2021-01-22
Received: 2020-07-09
Revision Accepted: 2020-10-15
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Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering
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Kejie Lu, Ying Qian, Jiaxing Gong, Ziyu Zhu, Jun Yin, Liang Ma, Mengfei Yu & Huiming Wang. Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering[J]. Journal of Zhejiang University Science D, 2021, 4(2): 258-277.
@article{title="Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering",
author="Kejie Lu, Ying Qian, Jiaxing Gong, Ziyu Zhu, Jun Yin, Liang Ma, Mengfei Yu & Huiming Wang",
journal="Journal of Zhejiang University Science D",
volume="4",
number="2",
pages="258-277",
year="2021",
publisher="Zhejiang University Press & Springer",
doi="10.1007/s42242-020-00104-5"
}
%0 Journal Article
%T Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering
%A Kejie Lu
%A Ying Qian
%A Jiaxing Gong
%A Ziyu Zhu
%A Jun Yin
%A Liang Ma
%A Mengfei Yu & Huiming Wang
%J Journal of Zhejiang University SCIENCE D
%V 4
%N 2
%P 258-277
%@ 1869-1951
%D 2021
%I Zhejiang University Press & Springer
%DOI 10.1007/s42242-020-00104-5
TY - JOUR
T1 - Biofabrication of aligned structures that guide cell orientation and applications in tissue engineering
A1 - Kejie Lu
A1 - Ying Qian
A1 - Jiaxing Gong
A1 - Ziyu Zhu
A1 - Jun Yin
A1 - Liang Ma
A1 - Mengfei Yu & Huiming Wang
J0 - Journal of Zhejiang University Science D
VL - 4
IS - 2
SP - 258
EP - 277
%@ 1869-1951
Y1 - 2021
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1007/s42242-020-00104-5
Abstract: The organized alignment of cells in various tissues plays a significant role in the maintenance of specific functions. To induce such an alignment, ideal scaffolds should simulate the characteristics and morphologies of natural tissues. aligned structures that guide cell orientation are used to facilitate tissue regeneration and repair. We here review how various aligned structures are fabricated, including aligned electrospun nanofibers, aligned porous or channeled structures, micropatterns and combinations thereof, and their application in nerve, skeletal muscle, tendon, and tubular dentin regeneration. The future use of aligned structures in tissue engineering is also discussed.
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