Journal of Zhejiang University SCIENCE B 2026 Vol.27 No.6 P.561-589

http://doi.org/10.1631/jzus.B2500252


Endocrine-disrupting chemicals in aquatic ecosystems and their impacts on aquatic organisms and humans with advances in detection and remediation


Author(s):  Tariq DILDAR, Yongcheng XUE, Wenxiao CUI, Mhd IKHWANUDDIN, Muhammad SHAFIQ, Hongyu MA

Affiliation(s):  1. Guangdong Provincial Key Laboratory of Marine Biotechnology, Shantou University, Shantou 515063, China more

Corresponding email(s):   mahy@stu.edu.cn

Key Words:  Endocrine-disrupting chemical, Bioaccumulation, Health risk, Biosensor-based detection, Hybrid activated carbon, N-doped carbon adsorbent


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Tariq DILDAR, Yongcheng XUE, Wenxiao CUI, Mhd IKHWANUDDIN, Muhammad SHAFIQ, Hongyu MA. Endocrine-disrupting chemicals in aquatic ecosystems and their impacts on aquatic organisms and humans with advances in detection and remediation[J]. Journal of Zhejiang University Science B, 2026, 27(6): 561-589.

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author="Tariq DILDAR, Yongcheng XUE, Wenxiao CUI, Mhd IKHWANUDDIN, Muhammad SHAFIQ, Hongyu MA",
journal="Journal of Zhejiang University Science B",
volume="27",
number="6",
pages="561-589",
year="2026",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B2500252"
}

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%A Muhammad SHAFIQ
%A Hongyu MA
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A1 - Yongcheng XUE
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A1 - Mhd IKHWANUDDIN
A1 - Muhammad SHAFIQ
A1 - Hongyu MA
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B2500252


Abstract: 
The increasing anthropogenic burden, driven by population growth and intensified industrial and agricultural practices, has led to the widespread release of endocrine-disrupting chemicals (EDCs) into aquatic ecosystems, with significant implications for both environmental and human health. Many studies have reported the concentrations and toxicological effects of EDCs in aquatic environments, but few have addressed detection methods and remediation techniques. This review aims to highlight the sources, dynamics, and bioaccumulation of EDCs in aquatic ecosystems, along with their toxic effects on aquatic species and associated health risks in humans. Additionally, we provide an overview of advanced detection and remediation techniques. Our review found that EDCs, particularly phthalates and bisphenols, included in industrial effluents, domestic waste, and agricultural runoff, are frequently discharged into aquatic bodies through human activities. EDCs are associated with various toxic effects in aquatic organisms, such as bioaccumulation, transgenerational effects, reduced growth, immunotoxicity, DNA damage, and abnormal hormonal release, which impair reproductive development. Among the detection methods, biosensors, surface-enhanced Raman spectroscopy (SERS), and nuclear magnetic resonance (NMR) spectroscopy are promising tools for EDC detection relative to conventional analytical methods in aquatic systems. Emerging remediation techniques, such as hybrid activated carbon systems and N-doped carbon-based adsorbents, are recommended for their high removal efficiency. This review serves as a valuable resource for advancing research on EDC toxicity, detection, and remediation technologies.

水生态系统中内分泌干扰物对水生生物和人类的影响及检测修复技术进展

Tariq DILDAR1,3,4, 薛永成2, 崔文晓1,3,4, Mhd IKHWANUDDIN3,4,5, Muhammad SHAFIQ6, 马洪雨1,3,4
1汕头大学广东省海洋生物技术重点实验室, 中国汕头, 515063
2广东省农业技术推广中心, 中国广州, 511499
3汕头大学广东省环南海地区重要海水养殖品种开发利用国际联合研究中心, 中国汕头, 515063
4汕头大学-马来西亚登嘉楼大学虾蟹贝类联合实验室, 中国汕头, 515063
5Higher Institute Centre of Excellence (HICoE), Institute of Tropical Aquaculture and Fisheries, Universiti Malaysia Terengganu, Kuala Nerus 21030, Malaysia
6汕头大学医学院临床药理学研究所, 中国汕头, 515041
摘要:在人口增长及工农业生产加剧的推动下,日益增加的人类活动促使内分泌干扰物(EDCs)被广泛释放到水生态系统中,对环境和人类健康产生了重大影响。已有诸多研究报道了EDCs在水环境中的浓度及其毒理学效应,但关于其检测方法和修复技术的研究仍然较少。本综述旨在系统阐述水生态系统中EDCs的来源、动力学和生物累积特征,并分析其对水生物种和人类健康的毒理学影响。此外,本综述还概述了先进的检测和修复技术。结果发现,EDCs(特别是邻苯二甲酸盐和双酚)常跟随工业废水、生活垃圾和农业径流经人类活动被排放到水体中。EDCs与水生生物的各种毒性效应密切相关,包括生物累积、跨代效应、生长减缓、免疫毒性、DNA损伤和异常激素释放,进而损害水生生物的生殖和发育功能。在检测技术方面,相比于传统方法,生物传感器、表面增强拉曼光谱和核磁共振光谱被认为是水环境中EDCs检测最具前景的三种技术。在新兴修复技术中,混合活性炭系统和氮掺杂碳吸附剂因其高效的去除能力而备受青睐。总之,本综述为促进水生态系统中EDCs的毒性机制研究,以及推动检测和修复技术发展提供了宝贵的参考资料。

关键词:内分泌干扰物;生物累积;健康风险;生物传感器检测;混合活性炭;氮掺杂碳吸附剂

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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On-line Access: 2026-06-23

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