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Abstract: exogenous lipoid pneumonia (ELP) following hydrocarbon aspiration is an unusual but severe condition. This study aimed to summarize the cases of pneumonitis following fuel aspiration from a single center to serve as a useful reference for clinicians in the future. The clinical courses and outcomes of 11 patients with pneumonitis following fuel aspiration were collected and presented. Among them, four representative cases were described in detail to summarize the management experience of this disease, and these cases were analyzed to better understand the clinical features and management strategies of hydrocarbon pneumonitis following fuel aspiration. Almost all patients were found to present with cough and dyspnea, and the most common symptoms were dyspnea and chest pain. A high proportion (90.9%) of patients presented with bilateral lower pulmonary field involvement, and half of the patients showed pneumonic consolidation. One patient with irreversible lung injury received extracorporeal membrane oxygenation (ECMO) and a lung transplant. The other patients received oxygen support, antibiotics, steroids, and other supportive care. Antibiotics and steroids were the most commonly used treatments. While bronchoalveolar lavage (BAL) was beneficial for removing irritants, its utility could also be reduced due to significant risks. Finally, all patients had favorable outcomes. In conclusion, ELP was definitely harmful to patients’ health, and hypoxemia was common among these patients. Supportive care, including antibiotics, steroids, and respiratory support, was the main treatment modality. It is recommended that the decision to employ BAL is made selectively. ECMO serves as a critical bridge to recovery or transplantation, and patients with timely and efficient treatment usually have a positive outcome.

燃料误吸继发外源性类脂性肺炎的临床管理策略：单中心诊疗经验总结

[1]Abd-ElmawlaMA, GhaiadHR, GadES, et al., 2023. Suppression of NLRP3 inflammasome by ivermectin ameliorates bleomycin-induced pulmonary fibrosis. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 24(8):723-733.

[2]ChangHY, ChenCW, ChenCY, et al., 1993. Successful treatment of diffuse lipoid pneumonitis with whole lung lavage. Thorax, 48(9):947-948.

[3]ChenYJ, HsuCC, ChenKT, 2019. Hydrocarbon pneumonitis following fuel siphonage: a case report and literature review. World J Emerg Med, 10(2):69-74.

[4]FengMX, LuYQ, 2021. Performance of extracorporeal membrane oxygenation in patients with fatal paraquat poisoning: grasp for straws? World J Emerg Med, 12(3):232-234.

[5]FranquetT, Gómez-SantosD, GiménezA, et al., 2000. Fire eater’s pneumonia: radiographic and CT findings. J Comput Assist Tomogr, 24(3):448-450.

[6]GregorioPHP, ToubatO, CrespoM, et al., 2025. Successful use of venopulmonary extracorporeal membrane oxygenation as a bridge to lung transplantation in a patient with idiopathic pulmonary arterial hypertension. J Cardiothorac Vasc Anesth, 39(10):2787-2793.

[7]GrossiE, CrisantiE, PolettiG, et al., 2006. Fire-eater’s pneumonitis. Monaldi Arch Chest Dis, 65(1):59-61.

[8]HaciomerogluO, EkinciGH, OngelEA, et al., 2014. Pneumonia caused by diesel fuel aspiration. J Coll Physicians Surg Pak, 24(Suppl 3):S272-S274.

[9]HaddaV, KhilnaniGC, BhallaAS, et al., 2009. Lipoid pneumonia presenting as non resolving community acquired pneumonia: a case report. Cases J, 2:9332.

[10]HarrisK, ChalhoubM, MarounR, et al., 2011. Lipoid pneumonia: a challenging diagnosis. Heart Lung, 40(6):580-584.

[11]JaybhayePL, ShilawantSS, 2014. Fatal case of hydrocarbon aspiration and use of lipoid cells as corroborative finding for rapid autopsy diagnosis in cases of delayed death. Toxicol Int, 21(3):316-318.

[12]KawashimaM, IjiriN, KonoedaC, et al., 2025. Extended use of central veno-arterial extracorporeal membrane oxygenation in lung transplantation for patients with pulmonary arterial hypertension. Eur J Cardiothorac Surg, 67(8):ezaf256.

[13]KhannaP, DevganSC, AroraVK, et al., 2004. Hydrocarbon pneumonitis following diesel siphonage. Indian J Chest Dis Allied Sci, 46(2):129-132.

[14]LeongWC, CheongBM, 2017. Siphoning diesel: a fatal mistake. Med J Malaysia, 72(5):314-315.

[15]LiDD, WangP, LuYQ, 2024. Successful extracorporeal membrane oxygenation-assisted treatment for a kidney transplant recipient infected with severe COVID-19. World J Emerg Med, 15(5):416-418.

[16]MaranguD, GrayD, VankerA, et al., 2020. Exogenous lipoid pneumonia in children: a systematic review. Paediatr Respir Rev, 33:45-51.

[17]SenV, KelekciS, Selimoglu SenH, et al., 2013. An evaluation of cases of pneumonia that occurred secondary to hydrocarbon exposure in children. Eur Rev Med Pharmacol Sci, 17(Suppl 1):9-12.

[18]ShresthaTM, BhattaS, BalayarR, et al., 2021. Diesel siphoner’s lung: an unusual cause of hydrocarbon pneumonitis. Clin Case Rep, 9(1):416-419.

[19]ShrivastavaMS, PalkarAV, KarnikND, 2011. Hydrocarbon pneumonitis masquerading as acute lung injury. BMJ Case Rep, 2011:bcr0320114017.

[20]VenkatnarayanK, MadanK, WaliaR, et al., 2014. “Diesel siphoner’s lung”: exogenous lipoid pneumonia following hydrocarbon aspiration. Lung India, 31(1):63-66.

[21]XieW, LiuWD, WangL, et al., 2024. Roles of THEM4 in the Akt pathway: a double-edged sword. J Zhejiang Univ-Sci B (Biomed & Biotechnol), 25(7):541-556.

[22]YiMS, KimKI, JeongYJ, et al., 2009. CT findings in hydrocarbon pneumonitis after diesel fuel siphonage. AJR Am J Roentgenol, 193(4):1118-1121.