Full Text:   <1620>

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CLC number: R69

On-line Access: 2016-09-07

Received: 2016-03-01

Revision Accepted: 2016-05-04

Crosschecked: 2016-08-08

Cited: 1

Clicked: 2895

Citations:  Bibtex RefMan EndNote GB/T7714

 ORCID:

Shi-cheng Yu

http://orcid.org/0000-0003-4617-3065

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Journal of Zhejiang University SCIENCE B 2016 Vol.17 No.9 P.722-727

http://doi.org/10.1631/jzus.B1600096


High-pressure balloon dilation for male anterior urethral stricture: single-center experience


Author(s):  Shi-cheng Yu, Hai-yang Wu, Wei Wang, Li-wei Xu, Guo-qing Ding, Zhi-gen Zhang, Gong-hui Li

Affiliation(s):  Department of Urology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   ligonghui1970@hotmail.com

Key Words:  Urethral stricture, High-pressure balloon dilation, Urethrotomy


Shi-cheng Yu, Hai-yang Wu, Wei Wang, Li-wei Xu, Guo-qing Ding, Zhi-gen Zhang, Gong-hui Li. High-pressure balloon dilation for male anterior urethral stricture: single-center experience[J]. Journal of Zhejiang University Science B, 2016, 17(9): 722-727.

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author="Shi-cheng Yu, Hai-yang Wu, Wei Wang, Li-wei Xu, Guo-qing Ding, Zhi-gen Zhang, Gong-hui Li",
journal="Journal of Zhejiang University Science B",
volume="17",
number="9",
pages="722-727",
year="2016",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.B1600096"
}

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%T High-pressure balloon dilation for male anterior urethral stricture: single-center experience
%A Shi-cheng Yu
%A Hai-yang Wu
%A Wei Wang
%A Li-wei Xu
%A Guo-qing Ding
%A Zhi-gen Zhang
%A Gong-hui Li
%J Journal of Zhejiang University SCIENCE B
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%D 2016
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1600096

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T1 - High-pressure balloon dilation for male anterior urethral stricture: single-center experience
A1 - Shi-cheng Yu
A1 - Hai-yang Wu
A1 - Wei Wang
A1 - Li-wei Xu
A1 - Guo-qing Ding
A1 - Zhi-gen Zhang
A1 - Gong-hui Li
J0 - Journal of Zhejiang University Science B
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SP - 722
EP - 727
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.B1600096


Abstract: 
Objectives: We retrospectively reviewed the urethral stricture cases treated in our tertiary center, and assessed the safety and feasibility of the high-pressure balloon dilation (HPBD) technique for anterior urethral stricture. Methods: From January 2009 to December 2012, a total of 31 patients with anterior urethral strictures underwent HPBD at our center, while another 25 cases were treated by direct vision internal urethrotomy (DVIU). Patient demographics, stricture characteristics, surgical techniques, and operative outcomes were assessed and compared between the two groups. The Kaplan-Meier survival analysis was applied to evaluate the stricture-free rate for the two surgical techniques. Results: The operation time was much shorter for the HPBD procedure than for the DVIU ((13.19±2.68) min vs. (18.44±3.29) min, P<0.01). For the HPBD group, the major postoperative complications as urethral bleeding and urinary tract infection (UTI) were less frequently encountered than those in DVIU (urethral bleeding: 2/31 vs. 8/25, P=0.017; UTI: 1/31 vs. 6/25 P=0.037). The Kaplan-Meier survival analysis showed that there was no significant difference in stricture-free rate at 36 months between the two groups (P=0.21, hazard ratio (HR)=0.65, 95% confidence interval (CI): 0.34 to 1.26). However, there was a significantly higher stricture-free survival in the HPBD group at 12 months (P=0.02, HR=0.35, 95% CI: 0.14 to 0.87), which indicated that the stricture recurrence could be delayed by using the HPBD technique. Conclusions: HPBD was effective and safe and it could be considered as an alternative treatment modality for anterior urethral stricture disease.

高压球囊扩张治疗男性前尿道狭窄:单中心的临床经验

目的:评估高压球囊扩张治疗男性前尿道狭窄的有效性和安全性。
创新点:既往高压球囊扩张技术已成熟应用于输尿管狭窄的临床治疗,我们将这一技术拓宽应用于男性前尿道狭窄的治疗,并证明高压球囊扩张治疗前尿道狭窄同样安全、有效。
方法:采用回顾性病例对照研究,收集并分析了31例接受高压球囊扩张和25例接受直视下尿道内切开术治疗的前尿道患者的病例资料,比较两组患者的手术时间、手术难易程度、术后并发症(出血和感染)、术后1年狭窄复发率和术后3年狭窄复发率等相关指标。
结论:高压球囊扩张组的手术时间和术后并发症发生率要优于直视下尿道内切开术组,两组患者的远期尿道狭窄复发率无统计学差异,但高压球囊扩张组的术后1年狭窄复发率明显低于直视下尿道内切开术组。高压球囊扩张治疗男性前尿道狭窄是安全、有效的,且近期疗效要优于传统腔内治疗方式。

关键词:尿道狭窄;高压球囊扩张;尿道内切开术

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article

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