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Journal of Zhejiang University SCIENCE A 2002 Vol.3 No.3 P.374-377

http://doi.org/10.1631/jzus.2002.0374


Ultra-Cut biopsy guided by ultrasonography for liver lesions: experience of 392 clinical cases


Author(s):  PAN Hong-ming, FAN xiao-ming, WANG Hai-yun, WU Jin-min

Affiliation(s):  Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   panhongming@163.net

Key Words:  Liver, Neoplasms, Biopsy, Ultrasonography


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PAN Hong-ming, FAN xiao-ming, WANG Hai-yun, WU Jin-min. Ultra-Cut biopsy guided by ultrasonography for liver lesions: experience of 392 clinical cases[J]. Journal of Zhejiang University Science A, 2002, 3(3): 374-377.

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author="PAN Hong-ming, FAN xiao-ming, WANG Hai-yun, WU Jin-min",
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publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2002.0374"
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%A PAN Hong-ming
%A FAN xiao-ming
%A WANG Hai-yun
%A WU Jin-min
%J Journal of Zhejiang University SCIENCE A
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%DOI 10.1631/jzus.2002.0374

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T1 - Ultra-Cut biopsy guided by ultrasonography for liver lesions: experience of 392 clinical cases
A1 - PAN Hong-ming
A1 - FAN xiao-ming
A1 - WANG Hai-yun
A1 - WU Jin-min
J0 - Journal of Zhejiang University Science A
VL - 3
IS - 3
SP - 374
EP - 377
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PB - Zhejiang University Press & Springer
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DOI - 10.1631/jzus.2002.0374


Abstract: 
We conducted a retrospective study of the accuracy of liver biopsies in 392 patients with liver lesions. Postbiopsy diagnosis was 297 cases of primary liver cancers, 79 cases of secondary malignant tumors, 2 cases of non-Hodgkin's lymphoma, 10 cases of focal nodular hyperplasia, 2 cases of chronic inflammation, 1 tuberculosis case and 1 schistosomiasis case. biopsy provided histological diagnosis in 100% of cases, sensibility and specificity of Ultra-Cut biopsy was 98.95% and 100% for the diagnosis of malignancy respectively; positive predictive value, 100%; negative predictive value, 71.43%; and accuracy, 98.98%. We identified no major procedure related complications despite the presence of thrombocytopenia in 37.5% of cases. Pain was the only reported adverse effect of liver biopsy (10.97%), and 11 patients required analgesics. We concluded that Ultra-Cut liver biopsy was a safe and effective technique, and was invaluable in the investigation and management of patients with liver lesions.

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Reference

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