Full Text:   <3217>

CLC number: R57

On-line Access: 

Received: 2007-10-11

Revision Accepted: 2008-02-29

Crosschecked: 0000-00-00

Cited: 8

Clicked: 7105

Citations:  Bibtex RefMan EndNote GB/T7714

-   Go to

Article info.
1. Reference List
Open peer comments

Journal of Zhejiang University SCIENCE B 2008 Vol.9 No.4 P.329-334


Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions

Author(s):  Guo-qiang XU, Yi-qun WU, Li-jun WANG, Hong-tan CHEN

Affiliation(s):  Department of Gastroenterology, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China; more

Corresponding email(s):   xuguoqi@mail.hz.zj.cn

Key Words:  Endoscopic ultrasonography (EUS), Duodenal protruding lesions, Diagnosis, Follow-up

Guo-qiang XU, Yi-qun WU, Li-jun WANG, Hong-tan CHEN. Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions[J]. Journal of Zhejiang University Science B, 2008, 9(4): 329-334.

@article{title="Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions",
author="Guo-qiang XU, Yi-qun WU, Li-jun WANG, Hong-tan CHEN",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions
%A Guo-qiang XU
%A Yi-qun WU
%A Li-jun WANG
%A Hong-tan CHEN
%J Journal of Zhejiang University SCIENCE B
%V 9
%N 4
%P 329-334
%@ 1673-1581
%D 2008
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B0710546

T1 - Values of endoscopic ultrasonography for diagnosis and treatment of duodenal protruding lesions
A1 - Guo-qiang XU
A1 - Yi-qun WU
A1 - Li-jun WANG
A1 - Hong-tan CHEN
J0 - Journal of Zhejiang University Science B
VL - 9
IS - 4
SP - 329
EP - 334
%@ 1673-1581
Y1 - 2008
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B0710546

Objective: The diagnoses of patients with duodenal protruding lesions are difficult when using conventional examinations such as computed tomography (CT) and conventional endoscope etc. Thus, we investigated the clinical value of endoscopic ultrasonography (EUS) with miniature ultrasonic probes on the diagnosis and treatment of duodenal protruding lesions. Methods: Patients with duodenal protruding lesions who were indicated for EUS were examined by EUS with 12~15 MHz miniature ultrasonic probes and double-cavity electronic endoscope. According to diagnosis of EUS, those patients were indicated for biopsy and treatment received biopsy, endoscopic resection or surgical excision. The postoperative histological results were compared with the preoperative diagnosis of EUS. Those patients without endoscopic resection or surgical excision were periodically followed up with EUS. Results: A total of 169 patients with duodenal protruding lesions were examined by EUS, of which 40 were diagnosed with cysts, 36 with inflammatory protruding or polyp, 25 with Brunner’s gland adenoma, 19 with ectopic pancreas, 17 with gastrointestinal stromal tumor, 12 with extrinsic compression, 12 with minor papilla, 6 with lipoma, 1 with adenocarcinoma and 1 with lymphoma. After EUS examinations, 75 patients received biopsy, endoscopic resection or surgical excision respectively. The postoperative histological results of 70 patients were completely consistent with the preoperative diagnosis of EUS, with 93.33% diagnostic accuracy. The results of follow-up with EUS indicated that duodenal cyst, Brunner’s gland adenoma, ectopic pancreas, gastrointestinal stromal tumor and lipoma remained unchanged within 1~3 years. No related complications occurred among all patients that received EUS examinations. Conclusion: EUS is an effective and reliable diagnostic method for duodenal protruding lesions.

Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


[1] Arguello, L., 2007. Endoscopic ultrasonography in submucosal lesions and extrinsic compressions of the gastrointestinal tract. Minerva Med., 98(4):389-393.

[2] Brand, B., Oesterhelweg, L., Binmoeller, K.F., Srirann, P.V., Bohnacker, S., Seewald, S., Weerth, A.D., Soehendra, N., 2002. Impact of endoscopic ultrasound for evaluation of submucosal lesions in gastrointestinal tract. Dig. Liver Dis., 34(4):290-297.

[3] Buscarini, E., Stasi, M.D., Rassi, S., Silva, M., Giangregorio, F., 1999. Endosonographic diagnosis of submucosal upper gastrointestinal tract lesions and large fold gastropathies by catheter probe. Gastrointest. Endosc., 49(2):184-191.

[4] Gourtsoyiannis, N., Grammatikakis, J., Prassopoulos, P., 2001. Role of conventional radiology in the diagnosis and staging of gastrointestinal tract neoplasms. Semin. Surg. Oncol., 20(2):91-108.

[5] Ichikawa, T., Kudo, M., Matsui, S., Okada, M., Kitano, M., 2007. Endoscopic ultrasonogrsphy with three miniature probes of different frequency is an accurate diagnostic tool for endoscopic submucosal of dissection. Hepatogastroenterology, 54(73):325-328.

[6] Izumi, Y., Inoue, H., Kawano, T., Tani, M., Tada, M., Okabe, S., Takeshita, K., Endo, M., 1999. Endosonography during endoscopic mucosal resection to enhance its safety: a new technique. Surg. Endosc., 13(4):358-360.

[7] Lau, S., Tam, K.F., Kam, C.K., Lui, C.Y., Siu, C.W., Lam, H.S., Mak, K.L., 2004. Imaging of gastrointestinal stromal tumors. Clin. Radiol., 59(6):487-498.

[8] Menzel, J., Domschke, W., 2000. Gastrointestinal miniprobe sonography: the current status. Am. J. Gastroenterol., 95(3):605-616.

[9] Okanobu, H., Hata, J., Haruma, K., Mitsuoka, Y., Kunihiro, K., Manabe, N., Tanaka, S., Chayama, K., 2005. A classification system of echogenicity for gastrointestinal neoplasm. Digestion, 72(1):8-12.

[10] Pfau, P.R., Chak, A., 2002. Endoscopic ultrasonography. Endoscopy, 34(1):21-28.

[11] Ponsaing, L.G., Kiss, K., Loft, A., Jensen, L.I., Hansen, M.B., 2007. Diagnostic procedures for submucosal tumors in the gastrointestinal tract. World J. Gastroenterol., 13(24):3301-3310.

[12] Rösch, T., 2003. Endoscopic ultrasonography: imaging and beyond. Gut, 52(8):1220-1226.

[13] Rösch, T., Kaper, B., Will, U., Baronius, W., Strobel, M., Lorenz, R., Ulm, K., 2002. Accuracy of endoscopic ultrasonography in upper gastrointestinal submucosal lesions: a prospective multicenter study. Scand. J. Gastroenterol., 37(7):856-862.

[14] Saftoiu, A., Vilmann, P., Ciurea, T., 2003. Utility of endoscopic ultrasound for the diagnosis and treatment of submucosal tumors of the upper gastrointestinal tract. Rom. J. Gastroenterol., 12(3):215-219.

[15] Shim, C.S., Jung, I.S., 2005. Endoscopic removal of submucosal tumors: preprocedure diagnosis, technical options and results. Endoscopy, 37(7):646-654.

[16] Waxman, I., Saitoh, Y., Raju, G.S., Watari, J., Yokota, K., Reeves, A.L., Kohgo, Y., 2002. High-frequency probe EUS-assisted endoscopic mucosal resection: a therapeutic strategy for submucosal tumor of the GI tract. Gastrointest. Endosc., 55(1):44-49.

[17] Wiech, T., Walch, A., Werner, M., 2005. Histopathological classification of nonneoplastic and neoplastic gastrointestinal submucosal lesions. Endoscopy, 37(7):630-634.

[18] Xu, G.Q., Li, Y.W., Han, Y.M., Li, Y.M., Chen, W.X., Ji, F., Li, H.J., Gu, Q., 2004. Miniature ultrasonic probes for diagnosis and treatment of digestive tract diseases. World J. Gastroenterol., 10:1948-1953.

[19] Xu, G.Q., Zhang, H., Li, Y.M., Chen, H.T., Ji, F., Chen, C.X., Ren, G.P., Ni, X.Y., 2006. Diagnosis and treatment of duodenal Brunner’s adenoma of 15 cases. Chin. J. Digest., 28(8):511-514 (in Chinese).

Open peer comments: Debate/Discuss/Question/Opinion


Please provide your name, email address and a comment

Journal of Zhejiang University-SCIENCE, 38 Zheda Road, Hangzhou 310027, China
Tel: +86-571-87952783; E-mail: cjzhang@zju.edu.cn
Copyright © 2000 - 2024 Journal of Zhejiang University-SCIENCE