CLC number: O69;S571.1
On-line Access:
Received: 2002-11-02
Revision Accepted: 2003-03-06
Crosschecked: 0000-00-00
Cited: 5
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CHEN Ping, TAN Yao, SUN Dong, ZHENG Xiao-ming. A novel long-chain acyl-derivative of epigallocatechin-3-O-gallate prepared and purified from green tea polyphenols[J]. Journal of Zhejiang University Science A, 2003, 4(6): 714-718.
@article{title="A novel long-chain acyl-derivative of epigallocatechin-3-O-gallate prepared and purified from green tea polyphenols",
author="CHEN Ping, TAN Yao, SUN Dong, ZHENG Xiao-ming",
journal="Journal of Zhejiang University Science A",
volume="4",
number="6",
pages="714-718",
year="2003",
publisher="Zhejiang University Press & Springer",
doi="10.1631/jzus.2003.0714"
}
%0 Journal Article
%T A novel long-chain acyl-derivative of epigallocatechin-3-O-gallate prepared and purified from green tea polyphenols
%A CHEN Ping
%A TAN Yao
%A SUN Dong
%A ZHENG Xiao-ming
%J Journal of Zhejiang University SCIENCE A
%V 4
%N 6
%P 714-718
%@ 1869-1951
%D 2003
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2003.0714
TY - JOUR
T1 - A novel long-chain acyl-derivative of epigallocatechin-3-O-gallate prepared and purified from green tea polyphenols
A1 - CHEN Ping
A1 - TAN Yao
A1 - SUN Dong
A1 - ZHENG Xiao-ming
J0 - Journal of Zhejiang University Science A
VL - 4
IS - 6
SP - 714
EP - 718
%@ 1869-1951
Y1 - 2003
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2003.0714
Abstract: lipophilic tea polyphenols (LTP) were prepared by catalytic esterifica tion of green tea polyphenols (GTP) with hexadecanoyl chloride. A novel long-ch a in acyl-derivative of epigallocatechin-3-o-gallate (EGCG) was first isol ated fro m purification of LTP by high-speed countercurrent chromatography (HSCCC) using a solvent system composed of n-hexane-ethyl acetate-methanol-water (1:1:1:1, v/v). The molecular structure of the acyl-derivative, Epigallocatechin-3-O- gall ate-4'-O-hexadecanate, was elucidated by means of elemental analysis, I R, 1H-NMR and MS spectra.
[1]Dreosti, I.E., 1996.Bioactive ingredients: antioxidants and polyphenols in tea.Nutr.Rev., 54(11):S51-S58.
[2]Hollman, P.C.H., Feskens, E.J.M.and Katan, M.B., 1999.Tea flavonols in cardiovascular disease and cancer epidemiology.Proc.Soc.Exp.Biol.Med., 2 20:198-202.
[3]Ito, Y.and Conway, W.D.(Editors), 1996.High-Speed Countercurrent Chromatography.Wiley-Interscience, New York.
[4]Jia, Z.S., Zhou, B., Yang, L., Wu, L.M.and Liu, Z.L., 1998.2D NMR study on tea polyphenols.Chin.J.Mag.Resonance, 15(1):23-30(in Chinese).
[5]Johnson, M.K.and Loo, G., 2000.Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA.Mutat.Res., 459:211-218.
[6]Li, H.C., Yashiki, S., Sonoda, J., Lou, H., Ghosh, S.K., Byrnes, J.J., Lema, C., Fujiyoshi, T., Karasuyama, M.and Sonoda, S., 2000.Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients.Jpn.J.Cancer.Res., 91:34-40.
[7]Liang, Y., Shen, S.R., Yang, X.Q., Zhao, B.L.and Hou, J.W., 1999.Antioxidant properties of lipophilic tea polyphenols.J.Zhejiang University(Agric.& Life Sci.), 25(5):529-534(in Chinese).
[8]Oka, F., Oka, H.and Ito, Y., 1991.Systematic search for suitable two-phase solvent systems for high-speed counter-current chromatography.J.Chromatogr., 538(1):99-108.
[9]Wang, Q.E., Tang, A.B., Ma, Z.H., Huang, W.and Shi, B., 2002.Synthesis of liposoluble tea polyphenols with varying aliphatic groups and their antioxidarion activity.Chin.Fine Chemicals, 19(2):86-89(in Chinese).
[10]Zhong, J.H., Chen, P., Zhang, G.Y., Wang, L.S.and Qian, J., 1999.A method of esterification production for lipophilic tea polyphenols.CN 1231277A(in Chinese).
[11]Zhu, N., Wang, M., Wei, G.J., Lin, J.K., Yang, C.S.and Ho, C.T., 2001.Identification of reaction products of (-)-epigallocatechin, (-)-epigallocatechin gallate and pyrogallol with 2,2-diphenyl-1-picrylhydrazyl radical.Food Chemistry, 73:345-349.
Open peer comments: Debate/Discuss/Question/Opinion
<1>
Daramola B@Federal Polytechnic , ado-ekiti Nigeria<daramola_bode@yahoo.co.uk>
2017-10-30 17:24:14
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2015-01-27 05:36:10
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