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CLC number: R540

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Received: 2003-03-03

Revision Accepted: 2003-03-28

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Journal of Zhejiang University SCIENCE A 2003 Vol.4 No.6 P.745-748


Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation

Author(s):  WANG Jian-an, SUN Yong, HE Hong

Affiliation(s):  Sir Run Run Shaw Hospital, Clinical Research Institute, Zhejiang University, Hangzhou 310016, China

Corresponding email(s):   wang_jian_an@163.net

Key Words:  Ultrasound ablation, Paroxysmal atrial fibrillation, Pulminary veins

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WANG Jian-an, SUN Yong, HE Hong. Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation[J]. Journal of Zhejiang University Science A, 2003, 4(6): 745-748.

@article{title="Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation",
author="WANG Jian-an, SUN Yong, HE Hong",
journal="Journal of Zhejiang University Science A",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation
%A WANG Jian-an
%A SUN Yong
%A HE Hong
%J Journal of Zhejiang University SCIENCE A
%V 4
%N 6
%P 745-748
%@ 1869-1951
%D 2003
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.2003.0745

T1 - Ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation
A1 - WANG Jian-an
A1 - SUN Yong
A1 - HE Hong
J0 - Journal of Zhejiang University Science A
VL - 4
IS - 6
SP - 745
EP - 748
%@ 1869-1951
Y1 - 2003
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.2003.0745

Objective: to evaluate the efficacy and safety of ultrasound ablation of pulmonary veins for treatment of paroxysmal atrial fibrillation. Methods: The study population consisted of 9 patients with 5 males and 4 females enrolled consecutively who had idiopathic paroxysmal atrial fibrillation (AF). The ultrasound balloon was positioned through a special sheath to the orifice of the target vein by a transseptal procedure. The balloon was inflated with contrast-mixed saline (contrast: saline = 1:4) whose volume was decided by the diameter of the target pulmonary vein. The ablation energy was usually set up at 35 to 40 watts with temperature controlled at 60°C. The duration of each ablation was about 120 seconds which was repeated not over 10 times. Results: The average duration of the total procedure was 132±68 min for our patients. The average fluoroscopy time was 33±17 min. With a mean follow-up of 16±8 months after the procedure, AF was completely eliminated in 4 patients without antiarrhythmic drugs. The episodes of atrial fibrillation were eliminated in 2 patients with low dosage of oral amiodarone (0.1, once daily) which was ineffective before the procedure. The frequency of episodes was similar to that before the procedure in 3 patients. There were no complications such as hemopericardium, air embolism and stenosis of the pulmonary veins by angiography, related to the procedure. Conclusion: ultrasound ablation of the pulmonary veins is a new approach to treat paroxysmal atrial fibrillation. Before we determined its value, we need to do more researches with bigger sample, randomization and comparison design.

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