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CLC number: R541.7

On-line Access: 2018-01-11

Received: 2016-11-27

Revision Accepted: 2017-05-01

Crosschecked: 2017-12-24

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Journal of Zhejiang University SCIENCE B 2018 Vol.19 No.1 P.57-64


Effect of corticosteroids on atrial fibrillation after catheter ablation: a meta-analysis#

Author(s):  Sanjay Jaiswal, Xian-bao Liu, Qu-cheng Wei, Ying-hao Sun, Li-han Wang, Liu-guang Song, Dan-dan Yang, Jian-an Wang

Affiliation(s):  Department of Cardiology, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

Corresponding email(s):   jian_an_wang@yahoo.com

Key Words:  Atrial fibrillation, Corticosteroids, Catheter ablation, Meta-analysis

Sanjay Jaiswal, Xian-bao Liu, Qu-cheng Wei, Ying-hao Sun, Li-han Wang, Liu-guang Song, Dan-dan Yang, Jian-an Wang. Effect of corticosteroids on atrial fibrillation after catheter ablation: a meta-analysis#[J]. Journal of Zhejiang University Science B, 2018, 19(1): 57-64.

@article{title="Effect of corticosteroids on atrial fibrillation after catheter ablation: a meta-analysis#",
author="Sanjay Jaiswal, Xian-bao Liu, Qu-cheng Wei, Ying-hao Sun, Li-han Wang, Liu-guang Song, Dan-dan Yang, Jian-an Wang",
journal="Journal of Zhejiang University Science B",
publisher="Zhejiang University Press & Springer",

%0 Journal Article
%T Effect of corticosteroids on atrial fibrillation after catheter ablation: a meta-analysis#
%A Sanjay Jaiswal
%A Xian-bao Liu
%A Qu-cheng Wei
%A Ying-hao Sun
%A Li-han Wang
%A Liu-guang Song
%A Dan-dan Yang
%A Jian-an Wang
%J Journal of Zhejiang University SCIENCE B
%V 19
%N 1
%P 57-64
%@ 1673-1581
%D 2018
%I Zhejiang University Press & Springer
%DOI 10.1631/jzus.B1600529

T1 - Effect of corticosteroids on atrial fibrillation after catheter ablation: a meta-analysis#
A1 - Sanjay Jaiswal
A1 - Xian-bao Liu
A1 - Qu-cheng Wei
A1 - Ying-hao Sun
A1 - Li-han Wang
A1 - Liu-guang Song
A1 - Dan-dan Yang
A1 - Jian-an Wang
J0 - Journal of Zhejiang University Science B
VL - 19
IS - 1
SP - 57
EP - 64
%@ 1673-1581
Y1 - 2018
PB - Zhejiang University Press & Springer
ER -
DOI - 10.1631/jzus.B1600529

Objective: The purpose of this meta-analysis was to explore the effect of corticosteroids on atrial fibrillation (AF) following catheter ablation. Methods: We searched PubMed, Embase, and the Cochrane Central Register of Controlled Trials for published articles describing the effect of corticosteroids in preventing AF recurrence after catheter ablation. Data on study and patient were extracted. Risk ratios (RRs) and 95% confidence intervals (CIs) were calculated by use of a random-effect model, and P values of <0.05 were considered significant. Results: Two randomized controlled trials (RCTs) and three cohort studies involving 846 patients were included in this meta-analysis. Within one month of catheter ablation, corticosteroid use was associated with a declined risk of recurrence of AF in RCT (RR 0.57, 95% CI 0.39 to 0.85, P=0.005), but without significant effect in cohort studies (RR 1.01, 95% CI 0.79 to 1.30, P=0.94). After three months of catheter ablation, corticosteroids did not have a significant effect in the prevention of late recurrence of AF in either RCT (RR 0.78, 95% CI 0.38 to 1.59, P=0.49) or cohort studies (RR 0.96, 95% CI 0.70 to 1.31, P=0.78). Conclusions: Our meta-analysis suggested that periprocedural administration of corticosteroids of catheter ablation was associated with reduction of early but not late recurrence of AF.




Darkslateblue:Affiliate; Royal Blue:Author; Turquoise:Article


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